Roxithromycin | CAS No. 80214-83-1

Roxithromycin

Basic Information

View in Editor

CAS Number

80214-83-1

Molecular Formula

C41H76N2O15

Molecular Weight

837.06 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Polymers and Plastics Thermoplastics Polyolefins

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Melting Point

111-118?C

Water Solubility

Soluble in water to 18µg/ml

Flash Point

>110°(230°F)

Solubility

chloroform: soluble10mg/mL

Specific Rotation

-90 ~ -96° (c=1, Acetone)

SMILES

View in Editor

CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O

InChI

InChI=1S/C41H76N2O15/c1-15-29-41(10,49)34(45)24(4)31(42-53-21-52-17-16-50-13)22(2)19-39(8,48)36(58-38-32(44)28(43(11)12)18-23(3)54-38)25(5)33(26(6)37(47)56-29)57-30-20-40(9,51-14)35(46)27(7)55-30/h22-30,32-36,38,44-46,48-49H,15-21H2,1-14H3/t22-,23-,24+,25+,26-,27+,28+,29-,30+,32-,33+,34-,35+,36-,38+,39-,40-,41-/m1/s1

InChIKey

RXZBMPWDPOLZGW-HITVVWEBSA-N

LogP

2.2096000000000067

Topological Polar Surface Area

216.89 Å²

Hydrogen Bond Donor/Acceptor

5 / 17

Complexity

1310

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Storage Conditions

2-8℃

Synonyms & References

English

Roxithromycin
9-(2, 5 dioxahexyloxyimino ) erythromycin
Assoral
As-soral} Claramid} Forilinj Overal
biaxsig
Brilid
Claramid
erythromycin 9-[0-[(2-methoxyethoxy) methyl]oxime]
Forilin
Overal
Rossi-trol
Rotramin
Roxid
roxyithromycin
RU 965
Rulid
Rulid f Surlid
Surlid
5-(3,4,6-Trideoxy-3-dimethylamino-beta-D-xylo-hexopyranosyloxy)-3-(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyloxy)-6,11,12-trihydroxy-9-(2-methoxyethoxy)methoxyimino-2,4,6,8,10,12-hex
5-(3,4,6-Trideoxy-3-dimethylamino-beta-D-xylo-hexopyranosyloxy)-3-(2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyloxy)-6,11,12-trihydroxy-9-(2-methoxyethoxy)methoxyimino-2,4,6,8,10,12-hexamethylpentadecan-13-olide
(3R,4S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyloxan-2-yl]
Assoral,Biaxsig,Brilid,Claramid,Forilin,Overal,Rossitrol,Rotramin,Roxacin,Roxar,Roxeptin,Roxibest-A,...
(3R,4S,5S,6R,7R,9R,11S,12R,13S,14R,E)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-7,12,13-trihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-10-(((2-methoxyethoxy)methoxy)imino)-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one

MDL Number

MFCD00214389

Customs Code

2941500000

FAQ

What is Roxithromycin (CAS: 80214-83-1)?

Roxithromycin is a macrolide antibiotic with the chemical formula C19H34N2O6. It is used to treat a variety of bacterial infections by inhibiting protein synthesis in bacteria. It is known for its broad-spectrum activity and is commonly prescribed for respiratory tract infections, skin infections, and other bacterial conditions.

What are the main uses of Roxithromycin (CAS: 80214-83-1)?

Roxithromycin is primarily used in the treatment of respiratory tract infections such as bronchitis, pneumonia, and pharyngitis. It is also effective against skin infections, urinary tract infections, and other bacterial infections. It is often prescribed as an alternative to erythromycin due to its improved pharmacokinetic profile.

Is Roxithromycin (CAS: 80214-83-1) safe?

Roxithromycin is generally considered safe when used as directed. Common side effects include gastrointestinal discomfort, such as nausea and diarrhea. It should be handled with care, following standard safety protocols for antibiotics to prevent resistance. Always consult a healthcare professional before use.

How should Roxithromycin (CAS: 80214-83-1) be stored?

Roxithromycin should be stored in a cool, dry place away from moisture and light. It is typically stable for up to 24 months when properly stored. Ensure the container is tightly closed and keep it out of reach of children to maintain its efficacy and safety.