Ketorolac tromethamine salt

Basic Information

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CAS Number

74103-07-4

Molecular Formula

C19H24N2O6

Molecular Weight

255.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

No data available

Melting Point

165.0 to 169.0 deg-C

Boiling Point

No data available

Flash Point

No data available

Solubility

H2O: 15 mg/mL stable at least one month at −20 °C., soluble

Vapor Pressure

No data available

SMILES

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C1CN2C(=CC=C2C(=O)C3=CC=CC=C3)C1C(=O)O.C(C(CO)(CO)N)O

InChI

InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)/t11-/m1/s1

InChIKey

OZWKMVRBQXNZKK-LLVKDONJSA-N

LogP

2.2910000000000004

Topological Polar Surface Area

59.3 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

430

Safety Information

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Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Synonyms & References

English

HMS502J18
KETOROLAC TROMETHAMINE (USP-RS)
Syntex
Ketorolac tromethamine (USAN:USP)
Ketorolac trometamol for peak identification, European Pharmacopoeia (EP) Reference Standard
NCGC00185990-04
MLS002222310
NCGC00261361-01
SR-01000946595-1
NCGC00094036-01
SPBio_001596
AKOS024386301
KBio2_004626
Prestwick2_000929
Prestwick0_000929
Acular LS
Prestwick3_000929
2-amino-2-(hydroxymethyl)propane-1,3-diol;5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
1H-PYRROLIZINE-1-1H-PYRROLIZINE-1-CARBOXYLIC ACID, 5-BENZOYL-2,3-DIHYDRO, (+/-)-, COMPOUND WITH 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL (1:1)
KETOROLAC TROMETHAMINE [VANDF]
Ketorolac tromethamine [USAN:USP]
NCGC00185990-01
CHEMBL1201124
Ketorolac Tromethamine;Ketorolac tris salt;RS37619 tromethamine salt
NSC758637
Tox21_110795_1
NCGC00094036-03
HMS2051P06
MFCD00887595
Toradol
Tromethamine ketorolac

MDL Number

MFCD00887595

Customs Code

2942000000

FAQ

What is Ketorolac tromethamine salt (CAS: 74103-07-4)?

Ketorolac tromethamine salt (CAS: 74103-07-4) is a nonsteroidal anti-inflammatory drug (NSAID) used primarily for pain relief. It is the tromethamine salt form of ketorolac, which is known for its potent analgesic and anti-inflammatory properties. The compound has a molecular formula of C16H15NO4S and is commonly used in pharmaceutical formulations due to its solubility and stability.

What are the main uses of Ketorolac tromethamine salt (CAS: 74103-07-4)?

Ketorolac tromethamine salt (CAS: 74103-07-4) is mainly used as a prescription medication for the treatment of moderate to severe pain. It is often administered in hospitals or clinics for postoperative pain management. Additionally, it is used in research for studying anti-inflammatory and analgesic mechanisms, and in pharmaceutical development for drug formulation purposes.

Is Ketorolac tromethamine salt (CAS: 74103-07-4) safe?

Ketorolac tromethamine salt (CAS: 74103-07-4) is generally considered safe when used as directed in medical settings. However, it may cause side effects such as gastrointestinal issues, allergic reactions, or renal impairment. Proper handling and adherence to safety guidelines are essential, especially during storage and administration. Always consult a healthcare professional for safe usage.

How should Ketorolac tromethamine salt (CAS: 74103-07-4) be stored?

Ketorolac tromethamine salt (CAS: 74103-07-4) should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 15°C to 25°C (59°F to 77°F) and in airtight containers to maintain its stability and potency. Avoid exposure to moisture and extreme temperatures to ensure proper shelf life and effectiveness.