7-(Trifluoromethyl)-4-chromanamine

Basic Information

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CAS Number

704208-25-3

Molecular Formula

C10H10F3NO

Molecular Weight

217.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

250℃

Density

1.289

Flash Point

105℃

SMILES

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C1COC2=C(C1N)C=CC(=C2)C(F)(F)F

InChI

InChI=1S/C10H10F3NO/c11-10(12,13)6-1-2-7-8(14)3-4-15-9(7)5-6/h1-2,5,8H,3-4,14H2

InChIKey

MMCIPVIZAJIRKM-UHFFFAOYSA-N

LogP

2.4877000000000002

Topological Polar Surface Area

35.25 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

231

Synonyms & References

English

704208-25-3
DTXSID80676388
AM20041050
FT-0718065
BCP27463
A15765
MFCD11656623
7-(trifluoromethyl)-3,4-dihydro-2H-chromen-4-amine
FT-0773468
FT-0772543
SB46541
SB46546
7-(trifluoromethyl)-3,4-dihydro-2H-1-benzopyran-4-amine
7-Trifluoromethyl-chroman-4-ylamine
CS-0197380
7-(trifluoromethyl)chroman-4-amine
I11125
MB10042
AS-49513
AKOS005146436
SCHEMBL1980281
2H-1-Benzopyran-4-amine,3,4-dihydro-7-(trifluoromethyl)-
(7-Trifluoromethylchroman-4-yl)amine
ACT06538
AG-G-74931
ANW-52781
CTK5D2367
SureCN1980281
MMCIPVIZAJIRKM-UHFFFAOYSA-N
EBD39005
0907AC

MDL Number

MFCD11656623

FAQ

What regulatory guidelines apply to 7-(Trifluoromethyl)-4-chromanamine (CAS: 704208-25-3)?

The compound 7-(Trifluoromethyl)-4-chromanamine (CAS: 704208-25-3) falls under the scope of the REACH regulations in the European Union, requiring registration for substances above one tonne per year. It may also be subject to GHS classification, which includes hazards such as flammability and environmental toxicity. FDA and EPA regulations might apply in the United States for pharmaceutical and environmental safety, respectively.

Are there alternatives to 7-(Trifluoromethyl)-4-chromanamine (CAS: 704208-25-3) in synthesis?

Several alternatives can be used in the synthesis of 7-(Trifluoromethyl)-4-chromanamine (CAS: 704208-25-3), such as 7-iodo-4-chromanamine, which can be deiodinated to form the target compound. Additionally, using different trifluoromethylating reagents like trifluoromethyl Grignard reagents can provide a more direct route to the compound.

What is the market or research trend for 7-(Trifluoromethyl)-4-chromanamine (CAS: 704208-25-3)?

Research on 7-(Trifluoromethyl)-4-chromanamine (CAS: 704208-25-3) is growing due to its potential use in medicinal chemistry as a functional group that can enhance drug properties. Market trends show increasing demand in pharmaceutical applications. Recent studies focus on its synthesis, reactivity, and biological evaluation.

How should waste containing 7-(Trifluoromethyl)-4-chromanamine (CAS: 704208-25-3) be handled?

Waste containing 7-(Trifluoromethyl)-4-chromanamine (CAS: 704208-25-3) should be collected and stored in leak-proof containers to prevent environmental contamination. Professional waste disposal is recommended, preferably through incineration or chemical treatment. Handling should follow local and national regulations to ensure environmental safety and compliance with legal requirements.