2-(Chloromethyl)quinazoline

Basic Information

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CAS Number

6148-18-1

Molecular Formula

C9H7ClN2

Molecular Weight

178.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

509.9°C at 760 mmHg

Density

1.278

Flash Point

262.2°C

Refractive Index

1.585

SMILES

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C1=CC=C2C(=C1)C=NC(=N2)CCl

InChI

InChI=1S/C9H7ClN2/c10-5-9-11-6-7-3-1-2-4-8(7)12-9/h1-4,6H,5H2

InChIKey

ZTXZPRVWTCOQNC-UHFFFAOYSA-N

LogP

2.3686

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

152

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

2-(Chloromethyl)quinazoline
5-[(4-chlorophenoxy)methyl]-3-[(4-methoxyphenyl)methyl]-1,2,4-oxadiazole
1,2,4-Oxadiazole, 5-[(4-chlorophenoxy)methyl]-3-[(4-methoxyphenyl)methyl]-
5-(4-Chloro-phenoxymethyl)-3-(4-methoxy-benzyl)-[1,2,4]oxadiazole
5-[(4-Chlorophenoxy)methyl]-3-(4-methoxybenzyl)-1,2,4-oxadiazole
2-chloromethylquinazoline
Quinazoline, 2-(chloromethyl)-
2-(chloromethyl)-quinazoline
ZTXZPRVWTCOQNC-UHFFFAOYSA-N
5270AJ
TRA0043671
FCH1167697
AB68878
AK209663
SY027936
CS-0085236
A833256
AC1447
DB-072966
MFCD13189671
SCHEMBL874900
2-(CHLOROMETHYL)QUINAZOLINE
AMY25849
AKOS027256980
DS-10196
6148-18-1

MDL Number

MFCD13189671

FAQ

What regulatory guidelines apply to 2-(Chloromethyl)quinazoline (CAS: 6148-18-1)?

2-(Chloromethyl)quinazoline (CAS: 6148-18-1) falls under various regulatory guidelines such as the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations in Europe, and requirements by the FDA and EPA in the United States. Manufacturers are required to follow specific labelling, storage, and disposal guidelines to ensure safety and compliance.

Are there alternatives to 2-(Chloromethyl)quinazoline (CAS: 6148-18-1) in synthesis?

There are alternative reagents that can be used in the synthesis of compounds similar to 2-(Chloromethyl)quinazoline (CAS: 6148-18-1). Options include using other quinazoline derivatives, such as 2-(bromomethyl)quinazoline, or employing different chlorinating agents. These alternatives can provide similar functionalities with varying degrees of reactivity and selectivity.

What is the market or research trend for 2-(Chloromethyl)quinazoline (CAS: 6148-18-1)?

The market for 2-(Chloromethyl)quinazoline (CAS: 6148-18-1) is primarily driven by its applications in pharmaceutical and agrochemical industries. Research trends include exploring its potential as an anticancer agent and as a pesticide. Additionally, there is increasing interest in its synthesis and properties due to its unique chemical structure and reactivity.

How should waste containing 2-(Chloromethyl)quinazoline (CAS: 6148-18-1) be handled?

Waste containing 2-(Chloromethyl)quinazoline (CAS: 6148-18-1) should be collected in appropriate containers and disposed of according to local regulations. Incineration is a common method for disposal, but professional waste disposal services should be used to ensure proper handling. Environmental precautions include minimizing exposure and following safety protocols to prevent contamination of soil and water.