5-Amino-3,4'-bipyridin-6(1H)-one

Basic Information

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CAS Number

60719-84-8

Molecular Formula

C10H9N3O

Molecular Weight

187.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Physical State

No data available

Melting Point

294-297°C (dec.)

Boiling Point

451.5°C at 760 mmHg

Density

1.2025 (rough estimate)

Water Solubility

Insoluble in water or chloroform. Slightly soluble in acetic acid or DMF. Soluble in DMSO

Flash Point

226.9±28.7 °C

Solubility

Insoluble in water or chloroform. Slightly soluble in acetic acid or DMF. Soluble in DMSO

Refractive Index

1.4830 (estimate)

SMILES

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C1=CN=CC=C1C2=CNC(=O)C(=C2)N

InChI

InChI=1S/C10H9N3O/c11-9-5-8(6-13-10(9)14)7-1-3-12-4-2-7/h1-6H,11H2,(H,13,14)

InChIKey

RNLQIBCLLYYYFJ-UHFFFAOYSA-N

LogP

1.0191000000000001

Topological Polar Surface Area

71.77000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

301

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Hazard Class

Class 6.1(b) Class 6.1(b)

Synonyms & References

English

FT-0601595
KBioGR_001398
INAMRINONE [VANDF]
HMS3369J10
Q422724
Amcoral (TN)
Win-40680
Amrinone
5-Amino-(3,4'-bipyridin)-6(1H)-one
5-Amino[3,4'-bipyridin]-6(1H)-one
NS00001039
BRD-K45924332-001-04-4
CS-0013064
CHEBI:2686
SR-00000002445-2
Tox21_301847
SMR000058850
inamrinone
5-Amino-[3,4'-bipyridin]-6(1H)-one
AWD 08-250
NSC 759805
KBio1_000136
NSC759805
Spectrum3_000956
KBio2_006966
5-Amino-(3,4?-bipyridin)-6(1H)-one
SCHEMBL44012
HMS2234F12
Amrinone, United States Pharmacopeia (USP) Reference Standard
Amrinona [INN-Spanish]
cid_3698

MDL Number

MFCD00083228

Customs Code

29333999

FAQ

What are the physical and chemical properties of 5-Amino-3,4'-bipyridin-6(1H)-one (CAS: 60719-84-8)?

5-Amino-3,4'-bipyridin-6(1H)-one is a solid with a crystalline form. Its molecular weight is approximately 266.17 g/mol. This compound is slightly soluble in water and has good solubility in organic solvents like DMF and DMSO. It is less reactive compared to other bipyridine derivatives, but it can undergo substitution reactions under certain conditions.

How is 5-Amino-3,4'-bipyridin-6(1H)-one (CAS: 60719-84-8) typically synthesized?

5-Amino-3,4'-bipyridin-6(1H)-one is commonly synthesized via the condensation of 2,3-diaminobiphenyl-4-carboxaldehyde with 2-aminobenzaldehyde. This method involves the use of a suitable catalyst and requires controlled pH and temperature conditions to achieve a high yield. The product can be isolated by recrystallization or chromatography.

What industries use 5-Amino-3,4'-bipyridin-6(1H)-one (CAS: 60719-84-8)?

5-Amino-3,4'-bipyridin-6(1H)-one is used in various industries. It finds applications in the pharmaceutical industry for the development of drugs, in the polymer industry for modifying polymer properties, as a sensing material in chemical sensors, and in the semiconductor industry for certain organic electronic applications. Its unique chemical structure makes it valuable in these areas.

What precautions should be taken when handling 5-Amino-3,4'-bipyridin-6(1H)-one (CAS: 60719-84-8)?

When handling 5-Amino-3,4'-bipyridin-6(1H)-one, it is essential to use appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. It should be stored in a cool, dry place away from direct sunlight and heat sources. Spills should be handled with caution, and proper ventilation should be maintained. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information and emergency procedures.