O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine

Basic Information

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CAS Number

5817-39-0

Molecular Formula

C15H12I3NO4

Molecular Weight

650.98 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

534.6 °C at 760 mmHg

Flash Point

9℃

Refractive Index

1.763

SMILES

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C1=CC(=C(C=C1CC(C(=O)O)N)I)OC2=CC(=C(C(=C2)I)O)I

InChI

InChI=1S/C15H12I3NO4/c16-9-3-7(4-12(19)15(21)22)1-2-13(9)23-8-5-10(17)14(20)11(18)6-8/h1-3,5-6,12,20H,4,19H2,(H,21,22)/t12-/m0/s1

InChIKey

HZCBWYNLGPIQRK-LBPRGKRZSA-N

LogP

3.9527000000000014

Topological Polar Surface Area

92.78 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

402

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H312 Harmful in contact with skin
Acute toxicity, dermal

H332 Harmful if inhaled
Acute toxicity, inhalation

Synonyms & References

English

3,3',5'-T3
L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo- (9CI)
4-(4-hydroxy-3,5-diiodophenoxy)-3-iodo-L-phenylalanine
REVERSE TRIIODOTHYRONINE
(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl]propanoic Acid (3,3',5'-Triiodo-L-Thyronine)
CHEBI:11684
3,3',5'-L-Triiodothyronine
5817-39-0
O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine
3,3 inverted exclamation marka,5 inverted exclamation marka-Triiodo-L-thyronine
Tox21_112797_1
CS-W011412
LEVOTHYROXINE SODIUM IMPURITY K [EP IMPURITY]
(S)-2-Amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl)propanoic acid
AKOS016843979
3,3,5-Triiodo-L-thyronine
AM83600
Alanine, 3-[4-(4-hydroxy-3,5-diiodophenoxy)-3-iodophenyl]-, L- (8CI)
Tox21_112797
SCHEMBL93385
3,3',5'-TRIIODOTHYRONINE, L-
8NZ4Y08T96
Levothyroxine Impurity K
3',5',3-Triiodothyronine
BDBM50103763
Q60998609
C07639
ALANINE, 3-(4-(4-HYDROXY-3,5-DIIODOPHENOXY)-3-IODOPHENYL)-, L-
3,3',5'-Triiodothyronine
NCGC00344545-01
DTXSID3046908

MDL Number

MFCD00036864

Customs Code

2922509090

FAQ

What regulatory guidelines apply to O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine (CAS: 5817-39-0)?

O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine (CAS: 5817-39-0) is regulated under various guidelines including the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) in the EU, and the Toxic Substances Control Act (TSCA) in the USA. Specific regulations may also include FDA and EPA requirements for safety handling and environmental protection.

Are there alternatives to O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine (CAS: 5817-39-0) in synthesis?

Synthesis alternatives to O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine (CAS: 5817-39-0) may include using related analogs or isomers such as O-(3,5-diiodophenyl)-3-iodotyrosine or other iodinated tyrosine derivatives. Common substituent reagents might include similar halogenated or iodinated compounds, but the choice depends on the specific application and desired properties.

What is the market or research trend for O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine (CAS: 5817-39-0)?

The market for O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine (CAS: 5817-39-0) is driven by its use in research for thyroid hormone modulation and as a potential drug candidate. Research trends include investigations into its biological activity and potential therapeutic applications, as well as efforts to develop more efficient synthesis methods and reduce costs.

How should waste containing O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine (CAS: 5817-39-0) be handled?

Waste containing O-(4-Hydroxy-3,5-diiodophenyl)-3-iodotyrosine (CAS: 5817-39-0) should be collected and disposed of according to regulatory guidelines. Incineration or professional waste disposal services are recommended to ensure environmental protection. Proper precautions should be taken to prevent contamination and ensure safe handling during waste collection and disposal processes.