4-(Hydroxymethyl)-2-methoxyphenol

Basic Information

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CAS Number

498-00-0

Molecular Formula

C8H10O3

Molecular Weight

154.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Physical State

Powder

Melting Point

110-117 °C

Boiling Point

313.1℃ at 760 mmHg

Water Solubility

Soluble in 95% ethanol (5 %), water, and oils.

Flash Point

143.2℃

Solubility

2 mg/mL at 20 °C

Refractive Index

1.4620 (estimate)

SMILES

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COc1cc(CO)ccc1O

InChI

InChI=1S/C8H10O3/c1-11-8-4-6(5-9)2-3-7(8)10/h2-4,9-10H,5H2,1H3

InChIKey

ZENOXNGFMSCLLL-UHFFFAOYSA-N

LogP

0.8930999999999998

Topological Polar Surface Area

49.69 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

116

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Stability

Stable. Incompatible with strong oxidizing agents, strong acids.

Sensitiveness

Sensitive to air

Synonyms & References

English

4-Hydroxy-3-methoxybenzyl alcohol
4-HYDROXYMETHYL-2-METHOXY-PHENOL
A 4-DIHYDROXY-3-METHOXYTOLUENE
FEMA 3737
RARECHEM AL BD 0101
VANILLYL ALCOHOL
4-hydroxy-3-methoxy-benzenemethano
4-hydroxy-3-methoxybenzyl
4-hydroxy-3-methoxybenzylalcohol(vanillicalcohol)
Benzenemethanol, 4-hydroxy-3-methoxy-
vanillol
VANILLYL ALCOHOL MI
Vanillyl alcohol (4-Hydroxy-3-methoxybenzyl alcohol)
Vanillyl
CITRONELLOL, D-(SG)
HOMOVANILLICALCOHOL
4-HYDROXY-3-METHOXYBENZENEMETHANOL
4-HYDROXY-3-METHOXYBENZYL ALCOHOL (VANILLYL ALCOHOL)
4-(Hydroxymethyl)-2-methoxyphenol
VANILLYL ALCOHOL(RG)
Vanillicalcohol
NSC 3993
Vanillin alcohol
Vanillic alcohol
4-hydroxy-3-methoxybenzylalcohol
3-Methoxy-4-hydroxybenzyl alcohol
4-Hydroxy-3-methoxyphenylmethanol
4-Hydroxy-3-methoxy-benzenemethanol
4-Hydroxy-3-methoxyphenyl methanol
4-(hydroxymethyl)-2-methoxy-phenol
V 0018 (alcohol)

MDL Number

MFCD00004659

Customs Code

29095090

FAQ

What is 4-(Hydroxymethyl)-2-methoxyphenol (CAS: 498-00-0)?

4-(Hydroxymethyl)-2-methoxyphenol, with the CAS number 498-00-0, is a phenolic compound containing hydroxymethyl and methoxy functional groups. It is commonly used as a precursor in the synthesis of various pharmaceuticals and organic materials. The chemical formula is C8H10O3, and it is typically a white solid with a mild aromatic odor.

What are the main uses of 4-(Hydroxymethyl)-2-methoxyphenol (CAS: 498-00-0)?

4-(Hydroxymethyl)-2-methoxyphenol is primarily used in pharmaceuticals as an intermediate for drug synthesis. It also finds applications in the production of antioxidants, flavor compounds, and specialty chemicals. In research, it is utilized for studying chemical reactivity and biological activities due to its functional group versatility.

Is 4-(Hydroxymethyl)-2-methoxyphenol (CAS: 498-00-0) safe?

4-(Hydroxymethyl)-2-methoxyphenol is generally considered safe when handled properly. However, it may cause irritation to the skin, eyes, and respiratory system. It is important to follow standard safety protocols, such as using gloves and ensuring proper ventilation. Safety data sheets (SDS) should be consulted for detailed handling and exposure information.

How should 4-(Hydroxymethyl)-2-methoxyphenol (CAS: 498-00-0) be stored?

4-(Hydroxymethyl)-2-methoxyphenol should be stored in a cool, dry, and well-ventilated area, away from light and moisture. It is best kept in a sealed, airtight container made of glass or plastic. Storage conditions should maintain a temperature below 25°C and low humidity to ensure stability and prevent degradation.