1-Amino-1-deoxy-D-glucitol

Basic Information

View in Editor

CAS Number

488-43-7

Molecular Formula

C6H15NO5

Molecular Weight

181.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Physical Properties

Melting Point

127 ºC

Boiling Point

314.29°C (rough estimate)

Flash Point

230 ºC

Refractive Index

-7 ° (C=10, H2O)

Specific Rotation

D15 -7.95° (c = 10 in water)

SMILES

View in Editor

C(C(C(C(C(CO)O)O)O)O)N

InChI

InChI=1S/C6H15NO5/c7-1-3(9)5(11)6(12)4(10)2-8/h3-6,8-12H,1-2,7H2/t3-,4+,5+,6+/m0/s1

InChIKey

SDOFMBGMRVAJNF-SLPGGIOYSA-N

LogP

-3.618999999999998

Topological Polar Surface Area

127.17 Å²

Hydrogen Bond Donor/Acceptor

7 / 6

Complexity

123

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

DTXSID901032334
NS00100246
(2R,3R,4R,5S)-6-aminohexane-1,2,3,4,5-pentol
D-Glucitol, 1-amino-1-deoxy-
A827611
D-Glucamine
Q27262753
GLUCAMINE [MI]
EC 207-677-3
1-amino-1-deoxy-glucitol
SDOFMBGMRVAJNF-SLPGGIOYSA-N
1-Amino-1-deoxy-D-sorbitol
5QN16UUF80
D90737
1-amino-1-desoxy-D-glucitol
W-109541
D-glucamin
(2R,3R,4R,5S)-6-Aminohexane-1,2,3,4,5-pentaol
D-Glucamine (>75%)
SCHEMBL2361
D-Glucamine (>75per cent)
AKOS016010317
GLUCAMINE [INCI]
1-Amino-1-deoxysorbitol
EINECS 207-677-3
GLUCAMINE
1-Amino-1-deoxy-glucosamine
1-amino-1-deoxyglucitol
D-Glucoamine
MFCD00077776
1-amino-desoxysorbitol

MDL Number

MFCD00077776

FAQ

What are the physical and chemical properties of 1-Amino-1-deoxy-D-glucitol (CAS: 488-43-7)?

1-Amino-1-deoxy-D-glucitol (CAS: 488-43-7) is a crystalline solid with a molecular weight of approximately 156.16 g/mol. It is slightly soluble in water and ethanol. Chemically, it exhibits basic properties due to the amino group, which can react with acids to form salts. It is also prone to dehydration, leading to the formation of sugars. This compound is used in the synthesis of various amino sugar derivatives and in pharmaceutical applications.

How is 1-Amino-1-deoxy-D-glucitol (CAS: 488-43-7) typically synthesized?

1-Amino-1-deoxy-D-glucitol (CAS: 488-43-7) can be synthesized through the reduction of 1-deoxy-D-glucitol with a suitable reducing agent like sodium borohydride in the presence of a solvent such as methanol. The reaction is conducted under mild conditions to ensure high selectivity and yield. This method is commonly used in academic and industrial settings for its simplicity and efficiency.

What industries use 1-Amino-1-deoxy-D-glucitol (CAS: 488-43-7)?

1-Amino-1-deoxy-D-glucitol (CAS: 488-43-7) is primarily used in the pharmaceutical industry for the synthesis of amino sugar derivatives. It also finds applications in the polymer industry as a precursor for the production of biodegradable polymers. Additionally, it is used in the development of sensors and as a component in semiconductor manufacturing processes.

What precautions should be taken when handling 1-Amino-1-deoxy-D-glucitol (CAS: 488-43-7)?

When handling 1-Amino-1-deoxy-D-glucitol (CAS: 488-43-7), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be performed in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.