2-Chloro-6-phenylpyrazine

Basic Information

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CAS Number

41270-62-6

Molecular Formula

C10H7ClN2

Molecular Weight

190.63 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

300.6±37.0°C at 760 mmHg

SMILES

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C1=CC=C(C=C1)C2=CN=CC(=N2)Cl

InChI

InChI=1S/C10H7ClN2/c11-10-7-12-6-9(13-10)8-4-2-1-3-5-8/h1-7H

InChIKey

XSCFGLUXJLGZJE-UHFFFAOYSA-N

LogP

2.7970000000000006

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

157

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

A825497
FT-0727759
Z1198163524
2-Chloro-6-phenylpyrazine
2-chloranyl-6-phenyl-pyrazine
A51078
SCHEMBL319173
DTXSID30410638
EN300-114841
XSCFGLUXJLGZJE-UHFFFAOYSA-N
2-Methoxy-4-methyl-1,3-thiazole-5-carboxylicacid
AKOS006278647
AMY41461
MFCD03861157
DS-6062
AC-9438
CS-0156385
41270-62-6
AB16842
J-508986
2-Chlor-6-phenylpyrazin
2-Chloro-6-phenyl-pyrazin
2-chloro-6-phenyl-pyrazine
6-chloro-2-phenylpyrazine
PubChem22086
5679AB
NE25761
AK112928
ST2404364
2-chloro-6-phenylpyrazine

MDL Number

MFCD03861157

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Chloro-6-phenylpyrazine (CAS: 41270-62-6)?

2-Chloro-6-phenylpyrazine is a solid with a crystalline form. Its molecular weight is approximately 208.18 g/mol. It has a low solubility in water but is soluble in organic solvents like ethanol and acetone. It is not highly reactive under normal conditions, but it can undergo substitution reactions under certain conditions. The compound is slightly yellow to brown in color.

How is 2-Chloro-6-phenylpyrazine (CAS: 41270-62-6) typically synthesized?

2-Chloro-6-phenylpyrazine is typically synthesized via the reaction of 6-aminophenylpyrazine with thionyl chloride in the presence of an appropriate solvent. The reaction is carried out at a moderate temperature, and the product can be isolated by recrystallization. This method provides good yield and high selectivity.

What industries use 2-Chloro-6-phenylpyrazine (CAS: 41270-62-6)?

2-Chloro-6-phenylpyrazine is used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs. It is also used in the sensor industry due to its specific chemical properties, which make it useful for detecting certain substances. Additionally, it has potential applications in the polymer industry for modifying the properties of polymers.

What precautions should be taken when handling 2-Chloro-6-phenylpyrazine (CAS: 41270-62-6)?

When handling 2-Chloro-6-phenylpyrazine, it is important to wear appropriate personal protective equipment (PPE), such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or in a fume hood to minimize exposure. Spills should be cleaned up promptly using appropriate absorbent materials. Safety data sheets (SDS) should be consulted for detailed information on handling and emergency procedures.