3,4-Dihydro-2H-pyran-2-ylmethanol

Basic Information

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CAS Number

3749-36-8

Molecular Formula

C6H10O2

Molecular Weight

114.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

101~102ºC

Boiling Point

93°C/25mmHg

Refractive Index

n20/D 1.478(lit.)<br />n20/D 1.479

SMILES

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C1CC(OC=C1)CO

InChI

InChI=1S/C6H10O2/c7-5-6-3-1-2-4-8-6/h2,4,6-7H,1,3,5H2

InChIKey

XMICBFRKICBBKD-UHFFFAOYSA-N

LogP

0.6714

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

88.5

Safety Information

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GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DHP linker
SCHEMBL186805
BCP21148
3,4-Dihydro-2H-Pyran-2-Methanol(DHP Linker)
NS00045855
A823700
D3295
XMICBFRKICBBKD-UHFFFAOYSA-
3,4-Dihydro-2H-pyran-2-methanol, >=98.5% (GC)
MFCD00051507
DTXSID301305096
AS-37619
FT-0635003
3749-36-8
NSC 20753
AKOS009158542
3,4-Dihydro-2H-pyran-2-ylmethanol
3,4-DIHYDRO-2-HYDROXYMETHYLPYRANE
SY257768
3,4-Dihydro-2H-pyran-2-methanol
M02893
hydroxymethyldihydro-pyran
2H-Pyran-2-methanol, 3,4-dihydro-
W-106532
2-Hydroxymethyl-3,4-dihydro-2H-pyran
SY051074
NSC20753
DHP Linker 3,4-Dihydro-2H-pyran-2- ylmethanol
SB22728
(3,4-dihydro-2H-pyran-2-yl)methanol
InChI=1/C6H10O2/c7-5-6-3-1-2-4-8-6/h2,4,6-7H,1,3,5H2

MDL Number

MFCD00051507

Customs Code

2932999099

FAQ

What are the physical and chemical properties of 3,4-Dihydro-2H-pyran-2-ylmethanol (CAS: 3749-36-8)?

3,4-Dihydro-2H-pyran-2-ylmethanol is a colorless liquid with a molecular weight of approximately 118.14 g/mol. It has a specific gravity of 0.992-0.994 g/cm³ and is miscible with water and ethanol. It reacts readily with carboxylic acids to form esters. It is sensitive to strong oxidizing agents and light.

How is 3,4-Dihydro-2H-pyran-2-ylmethanol (CAS: 3749-36-8) typically synthesized?

3,4-Dihydro-2H-pyran-2-ylmethanol can be synthesized via reduction of 3,4-dihydro-2H-pyran-2-one using sodium borohydride or lithium aluminum hydride as a reducing agent. The process involves controlling the reaction temperature and using a suitable solvent to ensure high yield and selectivity.

What industries use 3,4-Dihydro-2H-pyran-2-ylmethanol (CAS: 3749-36-8)?

3,4-Dihydro-2H-pyran-2-ylmethanol is used in the pharmaceutical industry for the synthesis of drugs, in the polymer industry for the production of various polymers, and in the chemical industry for manufacturing solvents and intermediates. It is also employed in the production of sensors and semiconductors.

What precautions should be taken when handling 3,4-Dihydro-2H-pyran-2-ylmethanol (CAS: 3749-36-8)?

When handling 3,4-Dihydro-2H-pyran-2-ylmethanol, ensure proper ventilation, use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat and direct sunlight. In case of spill, use appropriate spill kits and consult the Safety Data Sheet (SDS) for detailed instructions. Always work in a fume hood to minimize exposure risks.