1H-Imidazol-2-ylmethanol

Basic Information

View in Editor

CAS Number

3724-26-3

Molecular Formula

C4H6N2O

Molecular Weight

98.1 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

>160 ºC (dec.) (methanol water )

Boiling Point

388.1℃ at 760 mmHg

Flash Point

188.5 °C

SMILES

View in Editor

C1=CN=C(N1)CO

InChI

InChI=1S/C4H6N2O/c7-3-4-5-1-2-6-4/h1-2,7H,3H2,(H,5,6)

InChIKey

ZOMATQMEHRJKLO-UHFFFAOYSA-N

LogP

-0.09800000000000003

Topological Polar Surface Area

48.910000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

57.7

Synonyms & References

English

1H-Imidazol-2-ylmethanol
AR-527/43293956
hydroxymethylimidazole
FT-0694367
AB23143
Q27458557
(1H-Imidazol-2-yl)methanol
Z825761068
DTXSID30340729
2-hydroxymethylimidazole
SY041704
Imidazole-2-methanol
(1H-Imidazol-2-yl)-methanol
CS-0099374
2-(Hydroxymethyl)imidazol
3724-26-3
EN300-67317
MFCD06202766
A905757
AKOS005259805
2-(Hydroxymethyl)imidazole
(1H-Imidazol-2-yl)-methanol, AldrichCPR
BVG
1H-Imidazole-2-methanol
1H-Imidazol-2-ylmethanol #
2-(Hydroxymethyl)-1H-imidazole
AS-59047
AC-17832
AM807005
(1H-IMIDAZOL-2-YL)-METHANOL
1H-imidazol-2-ylmethanol

MDL Number

MFCD06202766

Customs Code

2933290090

FAQ

What are the physical and chemical properties of 1H-Imidazol-2-ylmethanol (CAS: 3724-26-3)?

1H-Imidazol-2-ylmethanol (CAS: 3724-26-3) is a colorless or white crystalline solid with a molecular weight of approximately 111.12 g/mol. It is poorly soluble in water but soluble in organic solvents like ethanol and acetone. Chemically, it is highly reactive due to the presence of a hydroxyl group and an imidazole ring, making it susceptible to protonation and substitution reactions.

How is 1H-Imidazol-2-ylmethanol (CAS: 3724-26-3) typically synthesized?

1H-Imidazol-2-ylmethanol (CAS: 3724-26-3) is synthesized by the condensation of 2-methylimidazole with methanol in the presence of a Lewis acid catalyst like aluminum trichloride. The reaction is carried out at room temperature, and the yield is typically around 70-80%, with good selectivity towards the desired product.

What industries use 1H-Imidazol-2-ylmethanol (CAS: 3724-26-3)?

1H-Imidazol-2-ylmethanol (CAS: 3724-26-3) finds application in various industries, including pharmaceuticals for use as a precursor in the synthesis of medicinal compounds, and in the production of polymers and sensors due to its reactivity and functional groups. It is also used in semiconductor manufacturing as a surface modifier.

What precautions should be taken when handling 1H-Imidazol-2-ylmethanol (CAS: 3724-26-3)?

When handling 1H-Imidazol-2-ylmethanol (CAS: 3724-26-3), it is essential to use personal protective equipment (PPE) such as gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood to avoid inhalation risks. Spills should be cleaned up using appropriate absorbent materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.