(1-methylpyrrolidin-2-yl)methanol

Basic Information

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CAS Number

3554-65-2

Molecular Formula

C6H13NO

Molecular Weight

115.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Boiling Point

164.8℃ at 760 mmHg

Flash Point

63.3℃

SMILES

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CN1CCCC1CO

InChI

InChI=1S/C6H13NO/c1-7-4-2-3-6(7)5-8/h6,8H,2-5H2,1H3

InChIKey

VCOJPHPOVDIRJK-UHFFFAOYSA-N

LogP

0.0728999999999998

Topological Polar Surface Area

23.47 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

74.9

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

EINECS 222-608-7
F8889-8364
2-Pyrrolidinemethanol, 1-methyl-
CHEBI:184330
NSC45497
A822863
[(2R)-1-methyl-2-pyrrolidinyl]methanol
1-Methylpyrrolidine-2-methanol
(1-Methyl-2-pyrrolidinyl)methanol #
2-hydroxymethyl-1-methylpyrrolidine
Crotonic acid, b-anilino-, ethyl ester
(S)-Methylpyrrolidine-2-methanol
SCHEMBL178545
N-methylprolinol
DTXSID20952956
W-106664
Z234895147
(2R)-1-Methyl-2-pyrrolidinemethanol
1-METHYL-2-PYRROLIDINEMETHANOL
MFCD07368622
NSC-45497
1-Methylpyrrolidinylmethanol
FT-0601402
MFCD06200823
AM20090536
1-methyl-2-pyrrolidinemethanol, AldrichCPR
BB 0262387
EN300-51076
(1)-1-Methylpyrrolidine-2-methanol
(1-methylpyrrolidin-2-yl)methanol
SY004710

MDL Number

MFCD06200823

FAQ

What regulatory guidelines apply to (1-methylpyrrolidin-2-yl)methanol (CAS: 3554-65-2)?

(1-methylpyrrolidin-2-yl)methanol (CAS: 3554-65-2) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) for hazardous properties such as flammability and skin irritation. In the EU, it is covered by REACH regulations, which require registration, evaluation, and authorization. Additionally, FDA and EPA have specific requirements for its use in pharmaceuticals and environmental releases, respectively.

Are there alternatives to (1-methylpyrrolidin-2-yl)methanol (CAS: 3554-65-2) in synthesis?

There are several alternatives to (1-methylpyrrolidin-2-yl)methanol (CAS: 3554-65-2) in synthesis, such as 2-pyrrolidinylmethanol or other tertiary amines. These can serve similar functional roles but may have different solubility, reactivity, and cost, depending on the specific application and synthesis conditions.

What is the market or research trend for (1-methylpyrrolidin-2-yl)methanol (CAS: 3554-65-2)?

The market for (1-methylpyrrolidin-2-yl)methanol (CAS: 3554-65-2) is growing due to its use in pharmaceuticals as a chiral auxiliary and in organic synthesis as a protecting group. Research trends include its application in developing new drug candidates and as a building block for synthetic chemistry. Price trends reflect increasing demand, but market fluctuations can occur based on supply chain dynamics and raw material availability.

How should waste containing (1-methylpyrrolidin-2-yl)methanol (CAS: 3554-65-2) be handled?

Waste containing (1-methylpyrrolidin-2-yl)methanol (CAS: 3554-65-2) should be collected in appropriate containers and stored in a well-ventilated area away from heat and ignition sources. It should be disposed of through professional waste disposal services to minimize environmental impact. Incineration or chemical neutralization may be used, but this must comply with local regulations and environmental protection standards.