6-Amino-7H-purin-2-ol

Basic Information

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CAS Number

3373-53-3

Molecular Formula

C5H5N5O

Molecular Weight

151.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Melting Point

300 ºC

Boiling Point

273.11°C (rough estimate)

Refractive Index

1.8000 (estimate)

SMILES

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C1=NC2=NC(=O)NC(=C2N1)N

InChI

InChI=1S/C5H5N5O/c6-3-2-4(8-1-7-2)10-5(11)9-3/h1H,(H4,6,7,8,9,10,11)

InChIKey

DRAVOWXCEBXPTN-UHFFFAOYSA-N

LogP

-0.8200000000000001

Topological Polar Surface Area

100.45 Å²

Hydrogen Bond Donor/Acceptor

4 / 6

Complexity

313

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

6-amino-3,9-dihydropurin-2-one
C74731
Q6085780
HY-124143
SR-01000637365-1
CCG-47772
AKOS015904753
SCHEMBL134675
NS00029534
6-Amino-1,3-dihydro-2H-purin-2-one
SCHEMBL432772
AKOS015854519
AKOS016008986
DTXSID00187406
6-Amino-2-hydroxypurine
6-amino-1,7-dihydropurin-2-one
2-Oxyadenine
FLUDARABINE PHOSPHATE IMPURITY B [EP IMPURITY]
NSC241501
DS-5009
UNII-E335PK4428
BDBM50497031
IGA
6-amino-7H-purin-2-ol
AMY38992
SY057869
AKOS015896923
Isoguanine
W-106766
I0370
AKOS006229677

MDL Number

MFCD00142931

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 6-Amino-7H-purin-2-ol (CAS: 3373-53-3)?

6-Amino-7H-purin-2-ol (CAS: 3373-53-3) is a crystalline solid with a molecular weight of approximately 164.19 g/mol. It has a high solubility in water and moderate solubility in ethanol. This compound is less reactive compared to other purines but can undergo base-catalyzed reactions. Its melting point is around 169°C, and it is stable under normal conditions but should be stored away from strong acids and bases.

How is 6-Amino-7H-purin-2-ol (CAS: 3373-53-3) typically synthesized?

6-Amino-7H-purin-2-ol can be synthesized through a condensation reaction of an appropriate purine derivative with an amine. This process often involves the use of mild base catalysts like sodium hydroxide or potassium carbonate. The reaction is carried out in an aqueous medium, and the yield is typically around 75-85%, with good selectivity towards the desired product.

What industries use 6-Amino-7H-purin-2-ol (CAS: 3373-53-3)?

6-Amino-7H-purin-2-ol (CAS: 3373-53-3) is used in the pharmaceutical industry for the synthesis of nucleoside analogs and antiviral drugs. It also finds applications in the production of sensors, where it can be used as a detection reagent. Additionally, it is used in semiconductor technology for certain chemical processes.

What precautions should be taken when handling 6-Amino-7H-purin-2-ol (CAS: 3373-53-3)?

When handling 6-Amino-7H-purin-2-ol (CAS: 3373-53-3), it is important to use personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from strong acids and bases. In the event of a spill, it should be cleaned up using absorbent materials, and the area should be adequately ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.