[4-(Benzyloxy)-3-methoxyphenyl]methanol

Basic Information

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CAS Number

33693-48-0

Molecular Formula

C15H16O3

Molecular Weight

244.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

71-73 °C

Boiling Point

347.2°C (rough estimate)

Refractive Index

1.5570 (estimate)

SMILES

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COC1=C(C=CC(=C1)CO)OCC2=CC=CC=C2

InChI

InChI=1S/C15H16O3/c1-17-15-9-13(10-16)7-8-14(15)18-11-12-5-3-2-4-6-12/h2-9,16H,10-11H2,1H3

InChIKey

PDBXFVPMVYQICB-UHFFFAOYSA-N

LogP

2.7665000000000006

Topological Polar Surface Area

38.69 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

226

Synonyms & References

English

3-METHOXY-4-(PHENYLMETHOXY)BENZENEMETHANOL
4-(Benzyloxy)-3-methoxy-benzyl Alcohol
3-methoxy-4-benzyloxybenzyl alcohol
A904044
(4-(benzyloxy)-3-methoxyphenyl)methanol
3-Methoxy-4-(benzyloxy)benzyl Alcohol
DTXSID10187376
(3-methoxy-4-phenylmethoxyphenyl)methanol
4-Benzyloxy-3-methoxybenzyl alcohol
(4-Benzyloxy-3-methoxyphenyl)methanol
3-(methoxy)-4-(benzyloxy)benzyl alcohol
BENZYL ALCOHOL, 4-(BENZYLOXY)-3-METHOXY-
DAlc2-H_000048
NSC-169518
4-(Benzyloxy)-3-methoxybenzyl Alcohol
Vanillyl Alcohol Benzyl Ether
4-benzyloxy3-methoxybenzylalcohol
MFCD00004640
4-O-benzyl vanillyl alcohol
4-(Benzyloxy)-3-methoxy-benzylAlcohol-d2
[4-(Benzyloxy)-3-methoxyphenyl]methanol #
NSC 169518
NS00029525
AKOS000247469
SCHEMBL698056
E83621
FT-0743563
CS-0140243
W7Z6QS9TZR
4-Benzyloxy-3-methoxybenzyl alcohol, 97%
33693-48-0

MDL Number

MFCD00004640

Customs Code

2909499000

FAQ

What are the physical and chemical properties of (4-(Benzyloxy)-3-methoxyphenyl)methanol (CAS: 33693-48-0)?

(4-(Benzyloxy)-3-methoxyphenyl)methanol (CAS: 33693-48-0) has a crystalline form and a molecular weight of approximately 265.29 g/mol. It is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. It exhibits good reactivity towards nucleophiles, making it useful in organic synthesis. Its solubility and reactivity make it suitable for a variety of chemical processes.

How is (4-(Benzyloxy)-3-methoxyphenyl)methanol (CAS: 33693-48-0) typically synthesized?

(4-(Benzyloxy)-3-methoxyphenyl)methanol (CAS: 33693-48-0) is typically synthesized via a multistep process involving protection of a hydroxy group, followed by coupling reactions, methylation, and deprotection. Common catalysts include palladium-based catalysts. The synthesis yields around 85-90%, and the process is selective and efficient.

What industries use (4-(Benzyloxy)-3-methoxyphenyl)methanol (CAS: 33693-48-0)?

(4-(Benzyloxy)-3-methoxyphenyl)methanol (CAS: 33693-48-0) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It is also used in the polymer industry for the production of certain polymers and in the electronics industry for semiconductor applications. Its versatility makes it valuable in these and other specialized industries.

What precautions should be taken when handling (4-(Benzyloxy)-3-methoxyphenyl)methanol (CAS: 33693-48-0)?

When handling (4-(Benzyloxy)-3-methoxyphenyl)methanol (CAS: 33693-48-0), it is important to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Work should be conducted in a fume hood to minimize inhalation risk. Spills should be cleaned up carefully, following proper environmental safety protocols. Always refer to the safety data sheet (SDS) for detailed instructions and emergency procedures.