(2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Basic Information

View in Editor

CAS Number

2946-39-6

Molecular Formula

C10H12BrN5O4

Molecular Weight

346.14 g/mol

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Solid

Melting Point

210-212 °C (dec.)

Boiling Point

717.7°C at 760 mmHg

Water Solubility

Soluble in DMSO, and DMF. Insoluble in water.

Flash Point

387.8°C

Refractive Index

1.6400 (estimate)

SMILES

View in Editor

C1=NC(=C2C(=N1)N(C(=N2)Br)C3C(C(C(O3)CO)O)O)N

InChI

InChI=1S/C10H12BrN5O4/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,13,14)/t3-,5-,6-,9-/m1/s1

InChIKey

VJUPMOPLUQHMLE-UUOKFMHZSA-N

LogP

-1.2175000000000005

Topological Polar Surface Area

139.54 Å²

Hydrogen Bond Donor/Acceptor

5 / 9

Complexity

367

Safety Information

View Safety Information

GHS Hazard Pictograms

H315

H319

H335

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Air Sensitive

Synonyms & References

English

Bromoadenosine
NSC 79213
SR-01000147759-1
EN300-212333
Adenosine, 8-bromo
2946-39-6
(2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
8-bromadenosine
(2R,3R,4S,5R)-2-(6-Amino-8-bromo-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
(4S,2R,3R,5R)-2-(6-amino-8-bromopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
8-Bromoadenosine, powder
VJUPMOPLUQHMLE-UUOKFMHZSA-N
GBA
NS00049146
DTXSID001021364
AM84901
CHEBI:2312
8-Bromo Adenosine
NSC-79213
85C9T4TXH2
CHEMBL1775009
EINECS 220-959-0
UNII-85C9T4TXH2
BDBM50454084
SR-01000147759
8-Bromoadenosine
SCHEMBL440925
Adenosine, 8-bromo-
AKOS001715167
8-Bromoadenine-9-beta-D-ribofuranoside
DS-4670

MDL Number

MFCD00005733

FAQ

What is (2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS: 2946-39-6)?

(2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is a complex organic compound with a purine structure. It is a chiral molecule with specific stereochemistry. This compound is characterized by its amino and bromo substituents, and its hydroxymethyl and tetrahydrofuran rings, making it a unique molecule with potential applications in pharmaceuticals and research.

What are the main uses of (2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS: 2946-39-6)?

(2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is primarily used in pharmaceutical research, particularly in the development of anti-cancer drugs and as a reagent in biochemistry and molecular biology experiments.

Is (2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS: 2946-39-6) safe?

(2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol is generally considered safe when handled with appropriate precautions. However, it should be stored away from heat, light, and moisture, and handled in a well-ventilated area to avoid inhaling dust or aerosols. Protective gear such as gloves and goggles is recommended.

How should (2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (CAS: 2946-39-6) be stored?

(2R,3R,4S,5R)-2-(6-amino-8-bromo-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to prevent moisture absorption. Ensure proper ventilation during handling and storage to minimize the risk of fire or explosion.