6-Quinolinecarbonitrile

Basic Information

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CAS Number

23395-72-4

Molecular Formula

C10H6N2

Molecular Weight

17.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Nitriles

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

133-134 ºC (methanol )

Boiling Point

323.7±15.0 ºC (760 Torr),

Flash Point

115.5±5.6 ºC,

SMILES

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N#Cc1ccc2ncccc2c1

InChI

InChI=1S/C10H6N2/c11-7-8-3-4-10-9(6-8)2-1-5-12-10/h1-6H

InChIKey

NIFLNJLWZZABMI-UHFFFAOYSA-N

LogP

0.16199999999999998

Topological Polar Surface Area

35.0 Å²

Hydrogen Bond Donor/Acceptor

3 / 1

Complexity

203

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Quinoline-6-carbonitrile
6-Cyanoquinoline
6-Quinolinecarbonitrile
6-Cyan-chinolin
Chinolin-6-carbonitril
NIFLNJLWZZABMI-UHFFFAOYSA-N
6-Cyano quinoline
6-Quinolinecarbonitrile #
quinoline-6-carbonitrile, AldrichCPR
RP21851
TRA0012416
SY024166
ST2413771
AB0023618
W4713

MDL Number

MFCD09999543

Customs Code

2933499090

FAQ

What regulatory guidelines apply to 6-Quinolinecarbonitrile (CAS: 23395-72-4)?

6-Quinolinecarbonitrile (CAS: 23395-72-4) is regulated under the Globally Harmonized System (GHS) for Classification and Labelling of Chemicals, and falls under the European Union's REACH regulations. In the United States, it is subject to the Environmental Protection Agency (EPA) and Food and Drug Administration (FDA) guidelines for chemical safety and environmental protection. Proper handling, storage, and disposal must comply with these regulations to ensure safety and legal compliance.

Are there alternatives to 6-Quinolinecarbonitrile (CAS: 23395-72-4) in synthesis?

Several alternatives can be used in the synthesis of 6-Quinolinecarbonitrile, including 2-aminoquinoline, 4-aminoquinoline, and 8-quinolinecarbonitrile. These compounds offer similar functionalities and can be used as substitutes depending on the specific application and reactivity requirements. Other common reagents include acetonitrile and various nitrile-containing compounds.

What is the market or research trend for 6-Quinolinecarbonitrile (CAS: 23395-72-4)?

The market for 6-Quinolinecarbonitrile is driven by its applications in pharmaceuticals, dyes, and organic synthesis. Research trends are focusing on its use as a key intermediate in the synthesis of antimalarial drugs and as a component in dye manufacturing. Recent studies also explore its role in developing new materials and its potential in environmental remediation.

How should waste containing 6-Quinolinecarbonitrile (CAS: 23395-72-4) be handled?

Waste containing 6-Quinolinecarbonitrile should be collected in appropriate containers and stored separately. It should be incinerated or disposed of by a professional waste management company that complies with local and international hazardous waste regulations. Environmental protection precautions include proper ventilation, personal protective equipment (PPE), and adherence to safety data sheet (SDS) recommendations to prevent environmental contamination and ensure worker safety.