4-Acridinol | CAS No. 18123-20-1

4-Acridinol

Basic Information

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CAS Number

18123-20-1

Molecular Formula

C13H9NO

Molecular Weight

195.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

114-118°C

Boiling Point

416.6°C at 760 mmHg

Density

1.307

Flash Point

205.7°C

Refractive Index

1.767

SMILES

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C1=CC=C2C(=C1)C=C3C=CC=C(C3=N2)O

InChI

InChI=1S/C13H9NO/c15-12-7-3-5-10-8-9-4-1-2-6-11(9)14-13(10)12/h1-8,15H

InChIKey

HOYZEVWRZVPHEL-UHFFFAOYSA-N

LogP

3.0936000000000012

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

231

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

BIDD:GT0415
FT-0692396
18123-20-1
Acridin-4-ol
EINECS 242-013-6
AS-11544
AKOS006228273
L6JFM786FB
4-Acridinol
4-Hydroxyacridine
NS00054465
MFCD00042743
A881007
HOYZEVWRZVPHEL-UHFFFAOYSA-N
SCHEMBL802228
4-hydroxy-acridine
DTXSID40171086
4-Hydroxy-acridin
4-HYDROXYACRIDINE
4-Hydroxyacridine Neooxine
5-hydroxyacridine
8-hydroxyacridine
KSC181E7J
AX8093478
ST2412618
AB0010291
ST51043413

MDL Number

MFCD00042743

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 4-Acridinol (CAS: 18123-20-1)?

4-Acridinol (CAS: 18123-20-1) is a crystalline solid with a molecular weight of approximately 168.16 g/mol. It is slightly soluble in water and highly soluble in organic solvents like ethanol and acetone. Chemically, it is a basic compound and exhibits reactivity towards acidic compounds, forming salts. It is stable under normal conditions but sensitive to strong oxidants.

How is 4-Acridinol (CAS: 18123-20-1) typically synthesized?

4-Acridinol (CAS: 18123-20-1) is commonly synthesized through the reduction of 4-acridone with sodium borohydride. The reaction is conducted in a basic medium, and the product is isolated by filtration and recrystallization. Other methods involve the reaction of acridone with hydrazine followed by hydrolysis, yielding 4-acridinol in moderate to good yield.

What industries use 4-Acridinol (CAS: 18123-20-1)?

4-Acridinol (CAS: 18123-20-1) is used in various industries. In pharmaceuticals, it serves as an intermediate for the synthesis of certain drugs. In the polymer industry, it is used as a stabilizer. It also finds applications in the production of sensors and semiconductors where its basic properties and reactivity are utilized.

What precautions should be taken when handling 4-Acridinol (CAS: 18123-20-1)?

When handling 4-Acridinol (CAS: 18123-20-1), wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Store the compound in a cool, dry place away from strong oxidants. In case of spill, handle it carefully using appropriate spill cleanup procedures and refer to the Safety Data Sheet (SDS) for detailed instructions.