(1-Methyl-1H-imidazol-4-yl)methanol

Basic Information

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CAS Number

17289-25-7

Molecular Formula

C5H8N2O

Molecular Weight

112.13 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

59.5-63.5

Boiling Point

324.9°C at 760 mmHg

Flash Point

150.3°C

Refractive Index

1.552

SMILES

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CN1C=C(N=C1)CO

InChI

InChI=1S/C5H8N2O/c1-7-2-5(3-8)6-4-7/h2,4,8H,3H2,1H3

InChIKey

NLEAEGDBKRBJAP-UHFFFAOYSA-N

LogP

-0.08760000000000007

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

76.8

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

1-Methyl-4-imidazolemethanol
BB 0260520
Z1137167436
SY020882
EN300-160479
1-methylimidazole-4-methanol
(1-Methyl-1H-imidazol-4-yl)-methanol
(1-methyl-1H-imidazol-4-yl)methanol, AldrichCPR
FT-0694120
SCHEMBL743854
AM803338
PB13038
(1-methyl-1H-imidazol-4-yl)methanol
F2135-1120
W-206046
CS-W006176
DS-13276
DTXSID00427612
1-methylimidazol-4-yl methanol
17289-25-7
MFCD06738905
NLEAEGDBKRBJAP-UHFFFAOYSA-N
(1-methylimidazol-4-yl)methanol
AKOS006282731
(1-Methyl-1H-imidazol-4-yl)methanol
1H-Imidazole-4-methanol,1-methyl-
4-(Hydroxymethyl)-1-methylimidazole
(1-Methyl-1H-imidazol-4-yl)methanol97%
RP00563

MDL Number

MFCD06738905

Customs Code

2933290090

FAQ

What are the physical and chemical properties of (1-Methyl-1H-imidazol-4-yl)methanol (CAS: 17289-25-7)?

(1-Methyl-1H-imidazol-4-yl)methanol (CAS: 17289-25-7) is a colorless liquid at room temperature. It has a molecular weight of approximately 124.14 g/mol and a solubility of up to 45 g/L in water at 25°C. This compound is known for its reactivity, particularly in nucleophilic substitution reactions. It is also a weak base and can participate in proton transfer reactions.

How is (1-Methyl-1H-imidazol-4-yl)methanol (CAS: 17289-25-7) typically synthesized?

(1-Methyl-1H-imidazol-4-yl)methanol (CAS: 17289-25-7) can be synthesized through a multistep process involving the condensation of 1-methylimidazole with methanol in the presence of a strong acid catalyst such as hydrochloric acid. The reaction typically provides a yield of over 70%, with high purity and selectivity.

What industries use (1-Methyl-1H-imidazol-4-yl)methanol (CAS: 17289-25-7)?

(1-Methyl-1H-imidazol-4-yl)methanol (CAS: 17289-25-7) is used in various industries, particularly in pharmaceuticals for its role as a precursor in drug synthesis. It also finds applications in the production of polymers and as a reagent in sensor technology and semiconductor manufacturing. Its versatile properties make it a valuable material in these sectors.

What precautions should be taken when handling (1-Methyl-1H-imidazol-4-yl)methanol (CAS: 17289-25-7)?

When handling (1-Methyl-1H-imidazol-4-yl)methanol (CAS: 17289-25-7), laboratory safety should be strictly maintained. Use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate methods, and the Material Safety Data Sheet (MSDS) should be referenced for detailed safety information and emergency procedures.