Sodium (3aR,4R,6R,6aR)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-olate 2-oxide | CAS No. 15718-49-7

Sodium (3aR,4R,6R,6aR)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-olate 2-oxide

Basic Information

CAS Number

15718-49-7

Molecular Formula

C10H11N5NaO7P

Molecular Weight

367.19 g/mol

AD

Basic Physical Properties

Solubility

H2O: soluble

C1=NC2=C(N1C3C4C(C(O3)CO)OP(=O)(O4)[O-])N=C(NC2=O)N.[Na+]

InChI

InChI=1S/C10H12N5O7P.Na/c11-10-13-7-4(8(17)14-10)12-2-15(7)9-6-5(3(1-16)20-9)21-23(18,19)22-6;/h2-3,5-6,9,16H,1H2,(H,18,19)(H3,11,13,14,17);/q;+1/p-1/t3-,5-,6-,9-;/m1./s1

InChIKey

KJPSSHNIEXRDDG-GWTDSMLYSA-M

LogP

-0.50470

Complexity

622

Synonyms & References

English

  • GUANOSINE 2/':3/'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • Guanosine-2',3'-cyclic monophosphate sodium salt
  • MFCD00070126
  • 2',3'-cGMP (sodium)
  • 15718-49-7
  • Guanosine 2',3'-cyclic monophosphate sodium salt
  • Guanosine 2':3'-cyclic monophosphate sodium salt
  • HY-N8245
  • CS-0140612
  • sodium;9-[(3aR,4R,6R,6aR)-6-(hydroxymethyl)-2-oxido-2-oxo-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-4-yl]-2-amino-1H-purin-6-one
  • GUANOSINE2:3-CYCLICMONOPHOSPHATESODIUMSALT
  • Guanosine, cyclic2',3'-(hydrogen phosphate), sodium salt (1:1)
  • GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT
  • 2':3'-Cycloguanosinphosphat
  • cyclic 2',3'-(hydrogen phosphate),monosodium salt
  • guanosine 2',3'-cyclic monophosphate sodium salt
  • guanosine 2',3'-cyclophosphate monosodium salt
  • Guanosine 2',3'-phosphatesodium salt
  • guanosine 2':3'-cyclic monophosphate*sodium
  • Guanosine,cyclic 2',3'-(hydrogen phosphate),monosodium salt
  • Natriumsalz

FAQ

What are the physical and chemical properties of Sodium (3aR,4R,6R,6aR)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-olate 2-oxide (CAS: 15718-49-7)?

This compound is a crystalline solid with a molecular weight of approximately 538.34 g/mol. It has low solubility in water but is soluble in organic solvents. It is reactive towards bases and can form complexes with metal ions. The compound is stable under normal laboratory conditions but should be stored in a well-ventilated area to prevent exposure to moisture and air.

How is Sodium (3aR,4R,6R,6aR)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-olate 2-oxide (CAS: 15718-49-7) typically synthesized?

The synthesis of this compound involves multi-step organic reactions such as nucleophilic substitution and condensation. It typically requires the use of Lewis acids and bases as catalysts. The yield and selectivity depend on the reaction conditions and the choice of reagents. Detailed procedures for synthesis can be found in the literature and are often reported in academic journals.

What industries use Sodium (3aR,4R,6R,6aR)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-olate 2-oxide (CAS: 15718-49-7)?

This compound is primarily used in pharmaceutical applications, particularly in the development of antiviral drugs. It may also have potential uses in polymer chemistry and as a sensor material due to its unique chemical properties. However, its specific applications are limited due to its complex structure and the challenges associated with its synthesis and handling.

What precautions should be taken when handling Sodium (3aR,4R,6R,6aR)-4-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-6-(hydroxymethyl)tetrahydrofuro[3,4-d][1,3,2]dioxaphosphol-2-olate 2-oxide (CAS: 15718-49-7)?

When handling this compound, it is essential to use personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated area or a fume hood to prevent inhalation of airborne particles. Spills should be cleaned up using appropriate absorbents, and the area should be thoroughly rinsed with water. Always consult the Safety Data Sheet (SDS) for detailed guidance on handling and storage.

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