2,6-Difluoronicotinaldehyde

Basic Information

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CAS Number

155601-65-3

Molecular Formula

C6H3F2NO

Molecular Weight

143.09 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Aldehydes

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

19-20℃

Boiling Point

234.0±35.0℃ at 760 mmHg

Flash Point

44.7℃

Refractive Index

1.4920

SMILES

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C1=CC(=NC(=C1C=O)F)F

InChI

InChI=1S/C6H3F2NO/c7-5-2-1-4(3-10)6(8)9-5/h1-3H

InChIKey

ZYCCUPSLEFLBNR-UHFFFAOYSA-N

LogP

1.1723000000000001

Topological Polar Surface Area

29.96 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

131

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Class KEEP COLD Class KEEP COLD

Class STORED UNDER ARGON Class STORED UNDER ARGON

Sensitiveness

Moisture Sensitive

Synonyms & References

English

W-205788
3-Pyridinecarboxaldehyde, 2,6-difluoro-
FT-0645853
EN300-1588630
2,6-Difluoronicotinaldehyde
2,6-difluoro-3-pyridinecarboxaldehyde
SCHEMBL623439
SY008074
AC-33273
CS-W003506
DTXSID30443628
2,6-difluoropyridine-3-carbaldehyde
SB52571
AM62454
2 pound not6-Difluoropyridine-3-carboxaldehyde
MFCD08277633
2,6-difluoropyridine-3-carbaldehyde;2,6-Difluoropyridine-3-carboxaldehyde
AKOS005063926
2,6-DIFLUOROPYRIDINE-3-CARBOXALDEHYDE
2,6-difluoro-pyridine-3-carbaldehyde
A809661
2,6-Difluoro-3-nicotinaldehyde
155601-65-3
PS-8997
ZYCCUPSLEFLBNR-UHFFFAOYSA-N
2,6-Difluoropyridine-3-carboxaldehyde
2,6-Difluoro-pyridin-3-carbaldehyde
2,6-Difluoropyridine-3-carboxaldehyd
2,6-difluoro-3-Pyridinecarboxaldehyde
3-Pyridinecarboxaldehyde, 2,6-difluoro- (9CI)
PubChem18894

MDL Number

MFCD08277633

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 2,6-Difluoronicotinaldehyde (CAS: 155601-65-3)?

2,6-Difluoronicotinaldehyde (CAS: 155601-65-3) is classified under the Globally Harmonized System (GHS) as a skin and eye irritant. In the European Union, it falls under REACH regulations, requiring manufacturers and importers to register the substance. FDA and EPA guidelines apply for its use in pharmaceuticals and environmental releases, respectively. Proper documentation and safety data sheets (SDS) must be maintained for compliance with these regulations.

Are there alternatives to 2,6-Difluoronicotinaldehyde (CAS: 155601-65-3) in synthesis?

Alternative reagents for synthesizing compounds similar to 2,6-Difluoronicotinaldehyde include 2,6-Difluoronicotinic acid and related derivatives. Isomers such as 2,5-Difluoronicotinaldehyde can also be considered. These alternatives may offer different reactivity profiles or properties, making them suitable for various synthesis pathways.

What is the market or research trend for 2,6-Difluoronicotinaldehyde (CAS: 155601-65-3)?

The market for 2,6-Difluoronicotinaldehyde (CAS: 155601-65-3) is growing due to its use in developing novel pharmaceuticals and agrochemicals. Research trends focus on exploring its biological activities and potential applications in cancer therapy. Price trends indicate a steady increase as demand for specialized intermediates in drug discovery rises. Emerging studies are also investigating its role in anti-inflammatory and neuroprotective treatments.

How should waste containing 2,6-Difluoronicotinaldehyde (CAS: 155601-65-3) be handled?

Waste containing 2,6-Difluoronicotinaldehyde (CAS: 155601-65-3) should be collected in sealed containers and handled according to local regulations. Proper incineration or professional waste disposal services should be used to ensure safe disposal. Environmental precautions include minimizing contact with water sources and ensuring adequate ventilation during handling to prevent exposure. Training and protective equipment are essential for safe waste management.