(4-Chloro-3,5-dimethyl-2-pyridinyl)methanol

Basic Information

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CAS Number

150054-50-5

Molecular Formula

C8H10ClNO

Molecular Weight

171.63 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

281.6±35.0 ºC (760 Torr),

Flash Point

124.1±25.9 ºC,

SMILES

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CC1=CN=C(C(=C1Cl)C)CO

InChI

InChI=1S/C8H10ClNO/c1-5-3-10-7(4-11)6(2)8(5)9/h3,11H,4H2,1-2H3

InChIKey

CQKHUAFREIMBJI-UHFFFAOYSA-N

LogP

1.8441399999999997

Topological Polar Surface Area

33.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

131

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

DS-12136
AKOS006312967
CS-0159874
C72854
2-Pyridinemethanol, 4-chloro-3,5-dimethyl-
4-chloro-2-hydroxymethyl-3,5-dimethylpyridine
4-Chloro-2-hydroxymethyl-3,5-Lutidine
2-HYDROXYMETHYL-3,5-DIMETHYL -4-CHLORO PYRIDINE
A910358
2-HYDROXYMETHYL-3,5-DIMETHYL-4-CHLOROPYRIDINE
DTXSID60430824
(4-CHLORO-3,5-DIMETHYLPYRIDIN-2-YL)METHANOL
CQKHUAFREIMBJI-UHFFFAOYSA-N
150054-50-5
SCHEMBL3180063
MFCD09859804
4-chloro-3,5-dimethyl-2-Pyridinemethanol
(4-chloro-3,5-dimethylpyridin-2-yl)methanol
2-Pyridinemethanol,4-chloro-3,5-dimethyl-
2-Hydroxy Methyl-3, 5-Dimethyl-4-Methoxy Pyridine.[Intermediate For Omeprazole]
2-Pyridinemethanol,4-chloro-3,5-dimethyl
4-CHLORO-3,5-DIMETHYL-2-HYDROXYMETHYLPYRIDINE
AK314762

MDL Number

MFCD09859804

FAQ

What are the physical and chemical properties of (4-Chloro-3,5-dimethyl-2-pyridinyl)methanol (CAS: 150054-50-5)?

(4-Chloro-3,5-dimethyl-2-pyridinyl)methanol (CAS: 150054-50-5) is a yellowish solid with a molecular weight of approximately 216.04 g/mol. It has a melting point of 85-87°C and is slightly soluble in water but more soluble in organic solvents. It is a reactive compound, showing reactivity towards nucleophiles and electrophiles. This compound is used in the synthesis of various medicinal and industrial chemicals.

How is (4-Chloro-3,5-dimethyl-2-pyridinyl)methanol (CAS: 150054-50-5) typically synthesized?

(4-Chloro-3,5-dimethyl-2-pyridinyl)methanol (CAS: 150054-50-5) can be synthesized through a multi-step process involving the reaction of dimethylaminopropyldimethylchlorosilane with 2-chloro-3,5-dimethylpyridine, followed by methanol treatment. This process yields the compound in high yield with good selectivity. The reaction typically requires a mild base and is performed under an inert atmosphere to prevent side reactions.

What industries use (4-Chloro-3,5-dimethyl-2-pyridinyl)methanol (CAS: 150054-50-5)?

(4-Chloro-3,5-dimethyl-2-pyridinyl)methanol (CAS: 150054-50-5) is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the development of sensors and as a precursor in the synthesis of various organic compounds. Its reactivity towards nucleophiles and electrophiles makes it valuable in both industrial and academic research.

What precautions should be taken when handling (4-Chloro-3,5-dimethyl-2-pyridinyl)methanol (CAS: 150054-50-5)?

When handling (4-Chloro-3,5-dimethyl-2-pyridinyl)methanol (CAS: 150054-50-5), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound is slightly toxic and corrosive, so it should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using appropriate absorbents, and the area should be flushed with water. Always refer to the safety data sheet (SDS) for specific guidance on handling and disposal.