6,9-Diazaspiro[4.5]decane dihydrochloride

Basic Information

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CAS Number

145122-55-0

Molecular Formula

C8H18Cl2N2

Molecular Weight

213.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

Boiling Point

314.2°Cat760mmHg

Flash Point

143.9°C

SMILES

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C1CCC2(C1)CNCCN2.Cl.Cl

InChI

InChI=1S/C8H16N2.2ClH/c1-2-4-8(3-1)7-9-5-6-10-8;;/h9-10H,1-7H2;2*1H

InChIKey

DXSGNKYVWDGHOR-UHFFFAOYSA-N

LogP

1.3355999999999995

Topological Polar Surface Area

24.06 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

116

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

AB29472
DXSGNKYVWDGHOR-UHFFFAOYSA-N
6,9-diaza-spiro[
6,9-Diazaspiro[4.5]decanedihydrochloride
AS-38116
145122-55-0
6,9-diazaspiro[4.5]decane;dihydrochloride
DTXSID50661367
AC-9260
EN300-222687
6,9-Diazaspiro[4.5]decane--hydrogen chloride (1/2)
VFA12255
AKOS025294518
6,9-Diaza-spiro[4.5]decane dihydrochloride
CS-0054994
6,9-Diaza-spiro[4.5]decanedihydrochloride
6,9-Diaza-spiro[4.5]decane DiHCl
MFCD06796600
A13133
6,9-Diazaspiro[4.5]decane, hydrochloride (1:2)
6,9-Diazaspiro[4.5]decane 2HCl
SCHEMBL994317
6,9-Diaza-spiro[4.5]decane 2HCl
6,9-Diazaspiro[4.5]decane dihydrochloride
6,9-Diazaspiro[4.5]decane,hydrochloride (1:2)
6,9-DIAZA-SPIRO[4.5]DECANE DIHYDROCHLORIDE
6,9-diazaspiro[4,5]decane dihydrochloride
6,9-diazaspiro< 4,5> decane dihydrochloride
A-1927
CTK8E5332
SureCN994317

MDL Number

MFCD06796600

FAQ

What are the physical and chemical properties of 6,9-Diazaspiro[4.5]decane dihydrochloride (CAS: 145122-55-0)?

6,9-Diazaspiro[4.5]decane dihydrochloride is a white to off-white crystalline solid. Its molecular weight is approximately 265.85 g/mol. It is slightly soluble in water and has a pKa of 1.5. This compound is highly reactive and can undergo ring-opening reactions under certain conditions.

How is 6,9-Diazaspiro[4.5]decane dihydrochloride (CAS: 145122-55-0) typically synthesized?

6,9-Diazaspiro[4.5]decane dihydrochloride is typically synthesized via ring-opening reactions of a cyclic amine followed by chlorination. Commonly, this involves condensation of 1,4-diazabicyclo[4.3.0]non-5-ene with an appropriate compound, followed by hydrochloric acid treatment to form the dihydrochloride salt.

What industries use 6,9-Diazaspiro[4.5]decane dihydrochloride (CAS: 145122-55-0)?

6,9-Diazaspiro[4.5]decane dihydrochloride finds applications in the pharmaceutical industry for its potential as a scaffold in drug design. It is also used in the chemical industry for the synthesis of other compounds and in the electronics industry for sensors and semiconductor applications.

What precautions should be taken when handling 6,9-Diazaspiro[4.5]decane dihydrochloride (CAS: 145122-55-0)?

When handling 6,9-Diazaspiro[4.5]decane dihydrochloride, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up using appropriate absorbents, and the area should be flushed with water. Always consult the Material Safety Data Sheet (MSDS) for specific safety information.