2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate

Basic Information

View in Editor

CAS Number

144222-22-0

Molecular Formula

C11H22N2O2

Molecular Weight

214.31 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Colorless to Yellow Liquid

Boiling Point

237-238 °C

Density

1.013 g/mL at 25 °C

Solubility

Soluble in chloroform and methanol.

Refractive Index

n20/D 1.473(lit.)

SMILES

View in Editor

CC(C)(C)OC(=O)N1CCC(CC1)CN

InChI

InChI=1S/C11H22N2O2/c1-11(2,3)15-10(14)13-6-4-9(8-12)5-7-13/h9H,4-8,12H2,1-3H3

InChIKey

KLKBCNDBOVRQIJ-UHFFFAOYSA-N

LogP

1.5922

Topological Polar Surface Area

55.56 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

215

Safety Information

View Safety Information

GHS Hazard Pictograms

H315

H319

H335

H400

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

4-aminomethyl-piperidine-1-carboxylic acid tert-butyl ester
N-tert-butyloxycarbonyl4-(aminomethyl)piperidine
tert-butyl 4-aminomethyl-1-piperidinecarboxylate
[1-(t-Butoxycarbonyl)piperidin-4-yl]methanamine
t-butyl 4-(aminomethyl)tetrahydropyridine-1(2H)-carboxylate
1-(tert-butoxycarbonyl)piperidin-4-ylmethylamine
CS-B0408
4-(Aminomethyl)-N-boc-piperidine
1-tert-Butoxycarbonyl-4-aminomethylpiperidine
1-tert-Butyloxycarbonyl-4-(aminomethyl)piperidine
tertiary butyl 4-(aminomethyl)piperidine-1-carboxylate
4-aminomethyl-1-n-(t-butoxycarbonyl)piperidine
HY-40007
tert-butyl 4-(aminomethyl)piperidine-1-carboxylate
tert-butyl-4-(aminomethyl)-piperidine-1-carboxylate
KLKBCNDBOVRQIJ-UHFFFAOYSA-N
4-Aminomethyl-1-tert-butoxycarbonylpiperidine
4-Aminomethyl-1-tert-butyloxycarbonylpiperidine
(1-tert-Butoxycarbonylpiperidin-4-yl)methylamine
tert-Butyl 4-aminomethylpiperidine-1-carboxylate
N-Boc-4-(aminomethyl)piperidine
SY007891
1-t-butyloxycarbonyl-4-aminomethylpiperidine
N-Boc-4-aminomethyl piperidine
4-(aminomethyl)-1-N-Boc piperidine
Q-102979
EN300-40882
4-Aminomethylpiperidine-1-carboxylic acid tert-butyl ester
4-(aminomethyl)piperidine-1-carboxylic acid tert-butyl ester
4-(Aminomethyl)-Boc-piperidine
1-(tert-butoxycarbonyl)piperidine-4-ylmethylamine

MDL Number

MFCD01076207

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate (CAS: 144222-22-0)?

2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate (CAS: 144222-22-0) is a crystalline solid with a molecular weight of approximately 234.33 g/mol. It has poor water solubility but better solubility in organic solvents like dichloromethane and ethanol. The compound is relatively stable but can react with strong acids and bases. It is a chiral molecule with optical activity.

How is 2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate (CAS: 144222-22-0) typically synthesized?

2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate (CAS: 144222-22-0) is synthesized through a multi-step process involving the reaction of 2-methyl-2-propanol and N-(4-(aminomethyl)piperidin-1-yl)carbonyl chloride in the presence of a suitable base like triethylamine. The reaction typically yields a high purity product with excellent selectivity and high yield.

What industries use 2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate (CAS: 144222-22-0)?

2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate (CAS: 144222-22-0) is primarily used in the pharmaceutical industry, particularly in the synthesis of various drug candidates. It is also utilized in the production of certain polymers and in developing sensors for detecting specific compounds.

What precautions should be taken when handling 2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate (CAS: 144222-22-0)?

When handling 2-Methyl-2-propanyl 4-(aminomethyl)-1-piperidinecarboxylate (CAS: 144222-22-0), it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using a suitable absorbent material, and proper disposal procedures should be followed. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.