2-(2,4-Dimethylthiazol-5-yl)ethanamine | CAS No. 142437-68-1

2-(2,4-Dimethylthiazol-5-yl)ethanamine

Basic Information

CAS Number

142437-68-1

Molecular Formula

C7H12N2S

Molecular Weight

156.25 g/mol

AD

Basic Physical Properties

CC1=C(SC(=N1)C)CCN

InChI

InChI=1S/C7H12N2S/c1-5-7(3-4-8)10-6(2)9-5/h3-4,8H2,1-2H3

InChIKey

VPRBZFPSDKDVFD-UHFFFAOYSA-N

LogP

1.2611400000000001

Topological Polar Surface Area

38.91 Ų

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

108

Synonyms & References

English

  • 2-(2,4-Dimethylthiazol-5-yl)ethanamine
  • LogP
  • 2-(2,4-Dimethyl-1,3-thiazol-5-yl)ethanamine
  • 2-(2,4-Dimethylthiazol-5-yl)ethamine
  • CS-0217273
  • CHEMBL553981
  • SY189619
  • 2-(2,4-dimethylthiazol-5-yl)ethan-1-amine
  • A3076
  • 142437-68-1
  • 2-(2,4-dimethyl-1,3-thiazol-5-yl)ethanamine
  • 2-(2,4-Dimethyl-5-thiazolyl)ethanamine
  • MFCD03011602
  • 2-(2,4-dimethylthiazol-5-yl)ethanamine
  • 2-(dimethyl-1,3-thiazol-5-yl)ethan-1-amine
  • DTXSID00576639
  • Oprea1_474108
  • BDBM50421966
  • 2-(2,4-Dimethyl-thiazol-5-yl)-ethylamine
  • 5-(2'-aminoethyl)-2,4-dimethylthiazole
  • Z1148766061
  • 2-(2,4-dimethyl-1,3-thiazol-5-yl)ethan-1-amine
  • AKOS006282740
  • SCHEMBL1244176
  • CHEMBL1195166
  • EN300-72582

MDL Number

MFCD03011602

FAQ

What are the physical and chemical properties of 2-(2,4-Dimethylthiazol-5-yl)ethanamine (CAS: 142437-68-1)?

2-(2,4-Dimethylthiazol-5-yl)ethanamine (CAS: 142437-68-1) is a crystalline solid with a molecular weight of approximately 218.24 g/mol. It has a melting point of 155-156°C and a boiling point of around 220°C. The compound is slightly soluble in water but more soluble in organic solvents like ethanol and acetone. It is a reactive amine, showing basic properties and can undergo substitution reactions and condensation reactions.

How is 2-(2,4-Dimethylthiazol-5-yl)ethanamine (CAS: 142437-68-1) typically synthesized?

2-(2,4-Dimethylthiazol-5-yl)ethanamine is typically synthesized via the reaction of 5-aminomethyl-2,4-dimethylthiazole with ethyl iodide. The reaction is carried out in the presence of a base like sodium hydroxide. The yield is generally good, and the product can be purified by recrystallization. This method ensures high purity and selectivity.

What industries use 2-(2,4-Dimethylthiazol-5-yl)ethanamine (CAS: 142437-68-1)?

2-(2,4-Dimethylthiazol-5-yl)ethanamine (CAS: 142437-68-1) is widely used in the pharmaceutical industry for its role as a key intermediate in the synthesis of various drugs. It is also utilized in the polymer industry for the production of functional polymers. Additionally, it is used in the sensor technology field, particularly in the fabrication of gas sensors and in semiconductor applications due to its unique electronic properties.

What precautions should be taken when handling 2-(2,4-Dimethylthiazol-5-yl)ethanamine (CAS: 142437-68-1)?

When handling 2-(2,4-Dimethylthiazol-5-yl)ethanamine (CAS: 142437-68-1), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be handled in a fume hood to minimize exposure. Spills should be carefully cleaned up with appropriate absorbents, and the area should be ventilated. It is crucial to consult the Safety Data Sheet (SDS) for detailed instructions and emergency procedures. This compound is not highly toxic, but direct contact with skin or inhalation can cause irritation.

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