5-Bromo-2-(difluoromethyl)-1,3-thiazole

Basic Information

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CAS Number

1319255-36-1

Molecular Formula

C4H2BrF2NS

Molecular Weight

214.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

188.7±40.0°C at 760 mmHg

SMILES

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FC(F)c1ncc(Br)s1

InChI

InChI=1S/C4H2BrF2NS/c5-2-1-8-4(9-2)3(6)7/h1,3H

InChIKey

RTILAKBVRIHMNT-UHFFFAOYSA-N

LogP

2.8432000000000004

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

103

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

5-Bromo-2-(difluoromethyl)thiazole
5-bromo-2-(difluoromethyl)-1,3-thiazole
Thiazole,5-bromo-2-(difluoromethyl)-
SB10728
PB37411
Thiazole, 5-bromo-2-(difluoromethyl)-
AK170786

MDL Number

MFCD23106373

FAQ

What is 5-Bromo-2-(difluoromethyl)-1,3-thiazole (CAS: 1319255-36-1)?

5-Bromo-2-(difluoromethyl)-1,3-thiazole (CAS: 1319255-36-1) is an organic compound with a molecular formula of C5H3BrF2NOS. It is a thiazole derivative characterized by its bromine and difluoromethyl substituents. This compound exhibits a yellow or orange crystalline appearance and is used in various applications, including pharmaceuticals and chemical synthesis.

What are the main uses of 5-Bromo-2-(difluoromethyl)-1,3-thiazole (CAS: 1319255-36-1)?

5-Bromo-2-(difluoromethyl)-1,3-thiazole (CAS: 1319255-36-1) is primarily used in the pharmaceutical industry as an intermediate for the synthesis of antiviral and antifungal agents. It is also utilized in chemical research for the preparation of other thiazole derivatives and as a reagent in organic synthesis.

Is 5-Bromo-2-(difluoromethyl)-1,3-thiazole (CAS: 1319255-36-1) safe?

5-Bromo-2-(difluoromethyl)-1,3-thiazole (CAS: 1319255-36-1) is generally considered safe when handled with appropriate precautions. However, it should be used in a well-ventilated area, and protective equipment such as gloves and safety goggles should be worn. Avoid contact with skin and eyes, and ensure proper disposal of waste materials.

How should 5-Bromo-2-(difluoromethyl)-1,3-thiazole (CAS: 1319255-36-1) be stored?

5-Bromo-2-(difluoromethyl)-1,3-thiazole (CAS: 1319255-36-1) should be stored in a cool, dry place away from direct sunlight and heat sources. It is recommended to store the compound in a sealed container to prevent exposure to moisture and air. The storage temperature should be maintained below 25°C to ensure stability.