(1-Methyl-1H-benzimidazol-5-yl)methanol

Basic Information

View in Editor

CAS Number

115576-91-5

Molecular Formula

C9H10N2O

Molecular Weight

162.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

View in Editor

CN1C=NC2=C1C=CC(=C2)CO

InChI

InChI=1S/C9H10N2O/c1-11-6-10-8-4-7(5-12)2-3-9(8)11/h2-4,6,12H,5H2,1H3

InChIKey

FNWIOHZJMSLWCF-UHFFFAOYSA-N

LogP

1.0655999999999999

Topological Polar Surface Area

38.05 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

163

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

(1-methyl-1H-benzo[d]imidazol-5-yl)methanol
EN300-1868806
FNWIOHZJMSLWCF-UHFFFAOYSA-N
A803457
115576-91-5
1H-Benzimidazole-5-methanol,1-methyl-(9CI)
(1-Methylbenzimidazol-5-yl)methanol;(1-Methyl-1H-benzo[d]imidazol-5-yl)methanol
MFCD11616105
DS-11302
DTXSID20561224
FT-0649791
AKOS006230048
(1-methylbenzimidazol-5-yl)methanol
(1-Methyl-1H-benzimidazol-5-yl)methanol
SCHEMBL541672
(1-methyl-1H-1,3-benzodiazol-5-yl)methanol
1H-Benzimidazole-5-methanol, 1-methyl-
5-Hydroxymethyl-1-methylbenzimidazole
(1-Methyl-1H-benzo[d]imidazol-5-yl)methanol
1H-Benzimidazole-5-methanol,1-methyl-
5-hydroxymethyl-1-methylbenzimidazole
(1-Methyl-1H-benzo[d]imidazol-5-yl)
(1-methyl-1H-benzimidazol-5-yl)methanol
(1-Methyl-1H-1,3-benzodiazol-5-yl)Methanol
(1-methyl-5-benzimidazolyl)methanol
2529AA
FCH831108
AX8157923
(1-methyl-1H-
(1-methyl-1H-1,3-benzodiazol-5-yl)m

MDL Number

MFCD11616105

Customs Code

2933990090

FAQ

What are the physical and chemical properties of (1-Methyl-1H-benzimidazol-5-yl)methanol (CAS: 115576-91-5)?

(1-Methyl-1H-benzimidazol-5-yl)methanol (CAS: 115576-91-5) is a colorless solid with a molecular weight of approximately 217.23 g/mol. It has a high solubility in organic solvents like methanol and ethanol but is only slightly soluble in water. This compound exhibits basic properties due to the presence of the amine group. It is a solid at room temperature and is known for its reactivity in nucleophilic substitution and condensation reactions.

How is (1-Methyl-1H-benzimidazol-5-yl)methanol (CAS: 115576-91-5) typically synthesized?

(1-Methyl-1H-benzimidazol-5-yl)methanol (CAS: 115576-91-5) can be synthesized through a multistep process starting from benzimidazole and methanol. A common method involves the protection of the amine group, followed by methylation, and finally deprotection to yield the desired product. This synthesis typically uses mild conditions and catalysts, ensuring high yield and selectivity.

What industries use (1-Methyl-1H-benzimidazol-5-yl)methanol (CAS: 115576-91-5)?

(1-Methyl-1H-benzimidazol-5-yl)methanol (CAS: 115576-91-5) finds applications in various industries, particularly in pharmaceuticals, where it serves as a building block for drug synthesis. It also has potential uses in the polymer industry, as a precursor for sensors, and in the semiconductor industry, where its unique properties can be utilized in certain processes.

What precautions should be taken when handling (1-Methyl-1H-benzimidazol-5-yl)methanol (CAS: 115576-91-5)?

When handling (1-Methyl-1H-benzimidazol-5-yl)methanol (CAS: 115576-91-5), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, use appropriate absorbent materials and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.