1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine

Basic Information

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CAS Number

1118786-90-5

Molecular Formula

C7H11N3O2

Molecular Weight

169.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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NCc1c(OC)ncnc1OC

InChI

InChI=1S/C7H11N3O2/c1-11-6-5(3-8)7(12-2)10-4-9-6/h4H,3,8H2,1-2H3

InChIKey

HWSNTMODDYZABZ-UHFFFAOYSA-N

LogP

-0.04750000000000054

Topological Polar Surface Area

70.26 Å²

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

122

Synonyms & References

English

4,6-Dimethoxypyrimidin-5-methylamine
(4,6-dimethoxypyrimidin-5-yl)methylamine
AC1Q4FBV
AG-B-75174
AK-39544
CTK7E3984
MolPort-015-134-337
(4,6-dimethoxypyrimidin-5-yl)methanamine
4,6-DIMETHOXYPYRIMIDIN-5-METHYL AMINE
AB0034775
X8986
ST24028698
1-(4,6-Dimethoxypyrimidin-5-yl)methanamine
1-(4,6-dimethoxypyrimidin-5-yl)methanamine

MDL Number

MFCD11858183

FAQ

What are the physical and chemical properties of 1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine (CAS: 1118786-90-5)?

1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine is a white crystalline solid with a molecular weight of approximately 246.21 g/mol. It has a slight solubility in water and ethanol. Chemically, it is relatively stable but can react with strong acids and bases. It is used in pharmaceutical and chemical synthesis applications.

How is 1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine (CAS: 1118786-90-5) typically synthesized?

1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine is synthesized through a multi-step process involving the condensation of 4,6-dimethoxy-5-pyrimidine with methylamine. Commonly, this involves the use of a mild base like triethylamine and is carried out in an organic solvent such as dichloromethane. The overall yield is typically around 70-80%, with good selectivity for the desired product.

What industries use 1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine (CAS: 1118786-90-5)?

1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine is used in the pharmaceutical industry as an intermediate for drug synthesis, particularly in the development of antiviral and anticancer drugs. It is also used in the polymer industry for the synthesis of functional polymers and in the sensor industry for developing chemical sensors.

What precautions should be taken when handling 1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine (CAS: 1118786-90-5)?

When handling 1-(4,6-Dimethoxy-5-pyrimidinyl)methanamine, it is important to wear appropriate personal protective equipment (PPE), such as gloves and safety goggles. This compound should be handled in a well-ventilated area or fume hood due to its potential to release vapors. In case of a spill, use appropriate spill cleanup materials and refer to the Safety Data Sheet (SDS) for detailed instructions. It is also advisable to store the compound in a cool, dry place away from direct sunlight and heat sources.