(1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol

Basic Information

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CAS Number

1065100-83-5

Molecular Formula

C8H8N2O

Molecular Weight

148.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1=CC2=C(NC=C2CO)N=C1

InChI

InChI=1S/C8H8N2O/c11-5-6-4-10-8-7(6)2-1-3-9-8/h1-4,11H,5H2,(H,9,10)

InChIKey

VWPSBHFXPGWHDI-UHFFFAOYSA-N

LogP

1.0552

Topological Polar Surface Area

48.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

140

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

(1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol
1H-Pyrrolo[2,3-b]pyridin-3-ylmethanol
1H-Pyrrolo[2,3-b]pyridine-3-methanol
{1H-pyrrolo[2,3-b]pyridin-3-yl}methanol
pyrrolobpyridinylmethanol
VWPSBHFXPGWHDI-UHFFFAOYSA-N
3-HYDROXYMETHYL-7-AZAINDOLE
RP09956
PB22460
AK100907
ST24020104
1H-pyrrolo[2,3-b]pyridin-3-ylmethanol
EN300-378759
DTXSID90655604
GEO-03584
MFCD11054203
SCHEMBL2217980
SY123658
DA-29333
AKOS005765979
J-500198
1065100-83-5
GE-0726
A895781
CS-0037417

MDL Number

MFCD11054203

Customs Code

2933990090

FAQ

What regulatory guidelines apply to (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS: 1065100-83-5)?

The regulatory guidelines for (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS: 1065100-83-5) include GHS classification, which categorizes it as a hazardous substance due to its potential toxicity. REACH regulations in the EU require manufacturers and importers to register the substance if it exceeds the threshold quantities. Additionally, the FDA and EPA have specific guidelines for the handling and disposal of this compound, focusing on its stability and potential environmental impact.

Are there alternatives to (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS: 1065100-83-5) in synthesis?

Yes, there are alternatives to (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS: 1065100-83-5) in synthesis, such as other pyridinylmethanol derivatives or related heterocycles like pyridine or pyrimidine. Common alternative reagents include substituted pyridines or pyrazines that can serve similar functional groups. These alternatives can offer different reactivity and selectivity profiles, making them suitable for specific synthetic routes.

What is the market or research trend for (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS: 1065100-83-5)?

The market for (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS: 1065100-83-5) is growing due to its applications in pharmaceuticals, specifically as intermediates in the synthesis of antiviral and anticancer drugs. Research trends are focused on developing more efficient synthesis methods and exploring its biological activity. Recent studies indicate increasing demand in the pharmaceutical industry, driven by the need for novel drug candidates.

How should waste containing (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS: 1065100-83-5) be handled?

Waste containing (1H-Pyrrolo[2,3-b]pyridin-3-yl)methanol (CAS: 1065100-83-5) should be handled by collection in appropriate containers and subsequent incineration or professional waste disposal. Environmental protection precautions include neutralizing the waste to minimize toxicity before disposal. It is crucial to follow local regulations and guidelines to ensure safe and compliant disposal, reducing the risk of environmental contamination and health hazards.