N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (1:1) | CAS No. 103878-83-7

N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (1:1)

Basic Information

CAS Number

103878-83-7

Molecular Formula

C8H11Cl2N3O

Molecular Weight

236.1 g/mol

AD

Basic Physical Properties

Melting Point

193-195°

C1=CC(=NC=C1Cl)C(=O)NCCN.Cl

InChI

InChI=1S/C8H10ClN3O.ClH/c9-6-1-2-7(12-5-6)8(13)11-4-3-10;/h1-2,5H,3-4,10H2,(H,11,13);1H

InChIKey

JMFKTFLARGGXCC-UHFFFAOYSA-N

LogP

0.8452999999999999

pKa

8.9(at 25℃)

Topological Polar Surface Area

68.00999999999999 Ų

Hydrogen Bond Donor/Acceptor

3 / 4

Complexity

177

Safety Information

View Safety Information

Toxicity

LD50 orally in mice: 1000-2000 mg/kg (Imhof, Kyburz, 1986)

Synonyms & References

English

  • NCGC00167737-01
  • 2-Pyridinecarboxamide, N-(2-aminoethyl)-5-chloro-, hydrochloride
  • SCHEMBL1230476
  • N-(2-Aminoethyl)-5-chlor-2-pyridincarbox
  • Lazabemide hydrochloride
  • Lazabemide monohydrochloride
  • 103878-83-7
  • N-(2-Aminoethyl)-5-chloropicolinamide monohydrochloride
  • n-(2-aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride
  • Tox21_112582_1
  • Ro 19-6327
  • Tox21_112582
  • EN300-267478
  • Pakio
  • CHEMBL2105029
  • CS-0002919
  • 2-Pyridinecarboxamide,N-(2-aminoethyl)-5-chloro-,hydrochloride(1:1)
  • CAS-103878-83-7
  • 2-Pyridinecarboxamide, N-(2-aminoethyl)-5-chloro-, monohydrochloride
  • AS-82197
  • D01097
  • Ro-19-6327/001
  • Lazabemide hydrochloride [USAN]
  • JMFKTFLARGGXCC-UHFFFAOYSA-N
  • Lazabemide HCl
  • LAZABEMIDE MONOHYDROCHLORIDE [MI]
  • N-(2-AMINOETHYL)-5-CHLORO-2-PYRIDINE-CARBOXAMIDE HYDROCHLORIDE
  • Ro 19-6327/001
  • N-(2-aminoethyl)-5-chloropyridine-2-carboxamide;hydrochloride
  • Lazabemide hydrochloride (JAN/USAN)
  • AKOS024457114

MDL Number

MFCD00878458

FAQ

What regulatory guidelines apply to N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (CAS: 103878-83-7)?

N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (CAS: 103878-83-7) is regulated under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) as a hazardous substance. Manufacturers and importers need to comply with REACH regulations in the European Union, ensuring that the substance is registered and classified correctly. In the USA, it is subject to FDA and EPA regulations for safety and environmental protection.

Are there alternatives to N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (CAS: 103878-83-7) in synthesis?

Yes, there are alternatives to N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (CAS: 103878-83-7) in synthesis, such as other pyridine derivatives and amino acid analogs. Common alternative reagents include 5-chloro-2-pyridinecarboxylic acid and its salts, which can be used to synthesize similar compounds with similar properties but potentially better handling characteristics.

What is the market or research trend for N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (CAS: 103878-83-7)?

The market for N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (CAS: 103878-83-7) is growing due to its applications in pharmaceutical and agricultural industries. Research trends focus on understanding its biological activity and developing more efficient synthesis methods. Price trends indicate a steady demand with minor fluctuations based on supply and demand dynamics.

How should waste containing N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (CAS: 103878-83-7) be handled?

Waste containing N-(2-Aminoethyl)-5-chloro-2-pyridinecarboxamide hydrochloride (CAS: 103878-83-7) should be collected in a secure, leak-proof container and stored away from heat and ignition sources. It is recommended to incinerate the waste under controlled conditions or dispose of it through a professional waste disposal service. Always follow local regulations for hazardous waste disposal to ensure environmental protection and safety.

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