How is [1-(2-Pyrazinylmethyl)-4-piperidinyl]methanol (CAS: 1247703-29-2) typically synthesized?

[1-(2-Pyrazinylmethyl)-4-piperidinyl]methanol can be synthesized by reacting 2-pyrazinylmethyl chloride with 4-piperidone in the presence of a base like sodium hydroxide in a suitable organic solvent. The reaction is typically carried out at room temperature, and the product is isolated by recrystallization from ethanol. The yield can reach up to 80%, and the reaction is selective under mild conditions.