Compound Q&A

How is 3-(1-Naphthyl)-1-propanamine (CAS: 24781-50-8) typically synthesized?

Answer

3-(1-Naphthyl)-1-propanamine
3-(1-Naphthyl)-1-propanamine (CAS: 24781-50-8) is typically synthesized via Hofmann rearrangement of N-aminonaphthalene. This process involves the reaction of naphthylamine with sodium hydroxide in a suitable solvent like ethanol. The yield is usually around 70-80%, and the reaction is carried out under basic conditions to ensure high selectivity and yield. Common catalysts include sodium or potassium hydroxide.

About

CAS No 24781-50-8
English Name 3-(1-Naphthyl)-1-propanamine
Molecular Formula C13H15N
Molecular Weight 185.27 g/mol
SMILES C1=CC=C2C(=C1)C=CC=C2CCCN
InChIKey XSNSJJCXHBHYNS-UHFFFAOYSA-N
Last Updated: 2026-04-01 19:31

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