Compound Q&A

How is 2-(4-Ethylphenoxy)-2-methylpropanoic acid (CAS: 17413-77-3) typically synthesized?

Answer

2-(4-Ethylphenoxy)-2-methylpropanoic acid
2-(4-Ethylphenoxy)-2-methylpropanoic acid is typically synthesized via a condensation reaction of 4-ethylphenol with 2-methylpropionyl chloride, catalyzed by a strong base such as sodium hydride. The yield is around 75-80%, and the reaction is carried out under anhydrous conditions to prevent hydrolysis.

About

CAS No 17413-77-3
English Name 2-(4-Ethylphenoxy)-2-methylpropanoic acid
Molecular Formula C12H16O3
Molecular Weight 208.26 g/mol
SMILES CCC1=CC=C(C=C1)OC(C)(C)C(=O)O
InChIKey HHHGHRABZLIUAT-UHFFFAOYSA-N
Last Updated: 2026-04-01 19:31

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