How is Ethyl 8-hydroxyimidazo[1,2-a]pyridine-2-carboxylate (CAS: 1041004-63-0) typically synthesized?

Ethyl 8-hydroxyimidazo[1,2-a]pyridine-2-carboxylate is typically synthesized through a multi-step process involving the reaction of ethyl 8-hydroxyimidazol-2(1H)-carboxylate with 2-chloro-1,3-dimethylimidazo[1,2-a]pyridine, followed by an intramolecular cyclization. The reaction is typically catalyzed by a Lewis acid such as aluminum trichloride, and the yield can be up to 78% with good selectivity.