Compound Q&A
How is (E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene (CAS: 19076-79-0) typically synthesized?
Answer
![(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene](https://static.chemtradehub.com/structs/190/19076-79-0-2542.webp "(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene")
(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene is synthesized via a multistep reaction involving bromination and subsequent alkylation. The reaction typically uses a catalytic amount of a Lewis acid, such as aluminum trichloride, and proceeds with good regioselectivity and enantioselectivity. The overall yield is moderate, around 50-70%, depending on the purity of starting materials and reaction conditions.
About
CAS No
19076-79-0
English Name
(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene
Molecular Formula
C24H24BrNO
Molecular Weight
422.36 g/mol
SMILES
CN(CCOc1ccc(cc1)C(=C(c1ccccc1)Br)c1ccccc1)C
InChIKey
IAJYQHATSIOBSH-UHFFFAOYSA-N
Last Updated: 2026-04-01 03:49
![(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene — Shanghai Jixiang Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce6f4d2b2de6e8e95a45bf/67ce6f4d2b2de6e8e95a45bf-logo.webp){kind=logo}
![(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene — HePeng （ ShangHai ） Biotechnology Co Ltd](https://static.chemtradehub.com/suppliers/67ceccf22b2de6e8e95a5e0f/67ceccf22b2de6e8e95a5e0f-logo.webp){kind=logo}
![(E,Z)-1-Bromo-2-[4-[2-(dimethylamino)ethoxy]phenyl]-1,2-diphenylethene — ShenZhenAiTaHuaXue Co Ltd](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fa/67ced0fb2b2de6e8e95a67fa-logo.webp){kind=logo}