Compound Q&A
How is 4-Methylaconitane-1,3,6,8,13,14,16,18-octol (CAS: 80787-51-5) typically synthesized?
Answer
4-Methylaconitane-1,3,6,8,13,14,16,18-octol (CAS: 80787-51-5) is synthesized through a series of reactions, including a Michael addition followed by a tandem esterification reaction. The process involves the use of a Cu(I) catalyst and requires a high level of purity in the starting materials. The overall yield is moderate, around 50-70%, and the reaction is selective towards the desired product.
About
CAS No
80787-51-5
English Name
4-Methylaconitane-1,3,6,8,13,14,16,18-octol; (1α,3α,6α,14α,16β)-form, O1,O6,O16,O18-Tetra-Me, N-Et, 14-O-(4-methoxybenzoyl), 3,8-di-Ac
Molecular Formula
C37H51NO12
Molecular Weight
701.800352334976 g/mol
SMILES
CCN1CC2(COC)C3C(OC)C4C1C3(C1CC3(O)C(OC(=O)c5ccc(OC)cc5)C1C4(CC3OC)OC(C)=O)C(CC2OC(C)=O)OC
InChIKey
QXHJUYOYZPRGCF-UHFFFAOYSA-N
Last Updated: 2026-04-01 03:49
