Compound Q&A

How is 8-Chloro-2,4(1H,3H)-quinazolinedione (CAS: 62484-22-4) typically synthesized?

Answer

8-Chloro-2,4(1H,3H)-quinazolinedione
8-Chloro-2,4(1H,3H)-quinazolinedione is commonly synthesized via the condensation of 2-amino-4-chloroquinazoline with acetic anhydride. This reaction typically proceeds with good yield and selectivity, but appropriate solvents and temperature control are necessary to achieve optimal results. The use of a catalytic amount of sulfuric acid can enhance the reaction rate and yield.

About

CAS No 62484-22-4
English Name 8-Chloro-2,4(1H,3H)-quinazolinedione
Molecular Formula C8H5ClN2O2
Molecular Weight 196.59 g/mol
SMILES C1=CC2=C(C(=C1)Cl)NC(=O)NC2=O
InChIKey AKXWCWNEEZHWFL-UHFFFAOYSA-N
Last Updated: 2026-04-01 03:49

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