Compound Q&A

How is 1-(2-Naphthyl)-1H-pyrrole-2,5-dione (CAS: 6637-45-2) typically synthesized?

Answer

1-(2-Naphthyl)-1H-pyrrole-2,5-dione
1-(2-Naphthyl)-1H-pyrrole-2,5-dione (CAS: 6637-45-2) can be synthesized through the condensation of 2-naphthylacetyl chloride with pyrrole. The reaction is typically carried out in the presence of a base like sodium hydride to facilitate the nucleophilic attack of pyrrole on the acetyl chloride group. The yield is usually high due to the favorable conditions and the high reactivity of the involved functional groups.

About

CAS No 6637-45-2
English Name 1-(2-Naphthyl)-1H-pyrrole-2,5-dione
Molecular Formula C14H9NO2
Molecular Weight 223.231 g/mol
SMILES O=C(C=C1)N(C2=CC=C3C=CC=CC3=C2)C1=O
InChIKey ISPTVBCAVIHHEF-UHFFFAOYSA-N
Last Updated: 2026-03-31 17:51

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