Compound Q&A
How is 1-[(3S)-4-(7-[6-Amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-{[(2S)-1-methyl-2-pyrrolidinyl]methoxy}-4-quinazolinyl)-3-methyl-1-piperazinyl]-2-propen-1-one (CAS: 2417987-45-0) typically synthesized?
Answer
![1-[(3S)-4-(7-[6-Amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-{[(2S)-1-methyl-2-pyrrolidinyl]methoxy}-4-quinazolinyl)-3-methyl-1-piperazinyl]-2-propen-1-one](https://static.chemtradehub.com/structs/241/2417987-45-0-24a9.webp "1-[(3S)-4-(7-[6-Amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-{[(2S)-1-methyl-2-pyrrolidinyl]methoxy}-4-quinazolinyl)-3-methyl-1-piperazinyl]-2-propen-1-one")
This compound is synthesized via a multi-step process involving the condensation of a pyridine derivative with a piperazine, followed by a series of substitutions and ring closures. The reaction is typically catalyzed by a transition metal complex and proceeds with high selectivity and yield.
About
CAS No
2417987-45-0
English Name
1-[(3S)-4-(7-[6-Amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-{[(2S)-1-methyl-2-pyrrolidinyl]methoxy}-4-quinazolinyl)-3-methyl-1-piperazinyl]-2-propen-1-one
Molecular Formula
C29H32ClF4N7O2
Molecular Weight
622.06 g/mol
SMILES
CN1CCC[C@H]1COC1=NC2=C(C=C(Cl)C(C3N=C(N)C=C(C)C=3C(F)(F)F)=C2F)C(=N1)N1CCN(C[C@@H]1C)C(=O)C=C
InChIKey
ZRBPIAWWRPFDPY-IRXDYDNUSA-N
Last Updated: 2026-03-29 08:05
![查看MedChemExpress LLC的1-[(3S)-4-(7-[6-Amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-{[(2S)-1-methyl-2-pyrrolidinyl]methoxy}-4-quinazolinyl)-3-methyl-1-piperazinyl]-2-propen-1-one](https://static.chemtradehub.com/suppliers/67ced0fb2b2de6e8e95a67fd/67ced0fb2b2de6e8e95a67fd-logo.webp){kind=logo}
![查看Shanghai Yuyeh Biotechnology Co., Ltd.的1-[(3S)-4-(7-[6-Amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-{[(2S)-1-methyl-2-pyrrolidinyl]methoxy}-4-quinazolinyl)-3-methyl-1-piperazinyl]-2-propen-1-one](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}