How is 4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide hydrochloride (CAS: 38059-78-8) typically synthesized?

4-Amino-5-chloro-N-[2-(diethylamino)ethyl]-2-hydroxybenzamide hydrochloride is typically synthesized via a multistep process involving the amidation of a 2-hydroxybenzamide with an amine, followed by the addition of diethylamine and chlorination. The reaction is catalyzed by an appropriate base in an organic solvent. The yield and selectivity of the reaction are high under optimized conditions, producing the desired hydrochloride salt.