Compound Q&A
How is Prednisolone-21-Carboxylic Acid (CAS: 61549-70-0) typically synthesized?
Answer
Prednisolone-21-Carboxylic Acid is synthesized through the conversion of prednisolone to its 21-carboxylic acid form. The process involves the removal of a methyl group from the C21 position of prednisolone. Common methods include catalytic hydrogenation followed by oxidation to form the carboxylic acid. This compound is synthesized with high selectivity and yields, making it a reliable intermediate for pharmaceutical applications.
About
CAS No
61549-70-0
English Name
Prednisolone-21-Carboxylic Acid
Molecular Formula
C21H26O6
Molecular Weight
374.4275 g/mol
SMILES
CC12CC(C3C(C1CCC2(C(=O)C(C(=O)O)O)O)CCC4=CC(=O)C=CC34C)O
InChIKey
FZHFGUJVTAMJKG-HRUPCHJUSA-N
Last Updated: 2026-03-28 23:48
