Compound Q&A

How is N-benzyl-2-chloro-N-phenylacetamide (CAS: 2653-14-7) typically synthesized?

Answer

N-benzyl-2-chloro-N-phenylacetamide
N-benzyl-2-chloro-N-phenylacetamide (CAS: 2653-14-7) is typically synthesized via a multi-step process involving the condensation of 2-chloroacetyl chloride with benzylamine and phenylacetic acid. The reaction is often catalyzed by a Lewis acid such as aluminum chloride. The yield is moderate to good, and the purity can be increased through recrystallization.

About

CAS No 2653-14-7
English Name N-benzyl-2-chloro-N-phenylacetamide
Molecular Formula C15H14ClNO
Molecular Weight 259.73600000000005 g/mol
SMILES ClCC(=O)N(Cc1ccccc1)c2ccccc2
InChIKey CFSKJDUGDLZDTI-UHFFFAOYSA-N
Last Updated: 2026-03-28 19:11

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