Compound Q&A

How is (4R)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one (CAS: 139264-24-7) typically synthesized?

Answer

(4R)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
(4R)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one is synthesized via a multi-step process involving the coupling of an indole derivative with an oxazolidinone via a palladium-catalyzed cross-coupling reaction. The reaction requires careful control of temperature and catalyst loading to achieve high yield and selectivity.

About

English Name (4R)-4-({3-[2-(Dimethylamino)ethyl]-1H-indol-5-yl}methyl)-1,3-oxazolidin-2-one
Molecular Formula C16H21N3O2
Molecular Weight 287.36 g/mol
SMILES CN(C)CCc1c[nH]c2c1cc(cc2)C[C@@H]3COC(=O)N3
InChIKey ULSDMUVEXKOYBU-CYBMUJFWSA-N
Last Updated: 2026-03-26 04:30

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