Compound Q&A

How is N6-Benzoyl-9-(2'-deoxy-5’-O-DMT-2’-fluoro-b-D-arabinofuranosyl)adenine 3’-CE-phosphoramidite (CAS: 329187-86-2) typically synthesized?

Answer

N6-Benzoyl-9-(2'-deoxy-5’-O-DMT-2’-fluoro-b-D-arabinofuranosyl)adenine 3’-CE-phosphoramidite
N6-Benzoyl-9-(2'-deoxy-5’-O-DMT-2’-fluoro-b-D-arabinofuranosyl)adenine 3’-CE-phosphoramidite is synthesized through a multi-step process involving the protection of the sugar, installation of the fluorescent label (DMT), and the introduction of the phosphoramidite functionality. This process often involves organic solvents and requires precise control over reaction conditions to achieve high yields and selectivity.

About

English Name N6-Benzoyl-9-(2'-deoxy-5’-O-DMT-2’-fluoro-b-D-arabinofuranosyl)adenine 3’-CE-phosphoramidite
Molecular Formula C47H51FN7O7P
Molecular Weight 17.03 g/mol
SMILES N#CCCOP(N(C(C)C)C(C)C)OC1C(COC(c2ccc(cc2)OC)(c2ccc(cc2)OC)c2ccccc2)OC(C1F)n1cnc2c1ncnc2NC(=O)c1ccccc1
InChIKey QGZKDVFQNNGYKY-UHFFFAOYSA-N
Last Updated: 2026-03-25 23:49

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