Compound Q&A
How is 4-(4-{[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-N-[(4-{[(2R)-1-(phenylsulfanyl)-4-(1-piperazinyl)-2-butanyl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamide (CAS: 2143096-93-7) typically synthesized?
Answer
![4-(4-{[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-N-[(4-{[(2R)-1-(phenylsulfanyl)-4-(1-piperazinyl)-2-butanyl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamid
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This compound is typically synthesized through multistep reactions involving the coupling of piperazine derivatives, phenylsulfanyl-substituted butyl amines, and cyclohexenone derivatives. The synthesis involves the use of catalysts and protecting groups to ensure high selectivity and yield, with typical yields ranging from 50-70%.
About
CAS No
2143096-93-7
English Name
4-(4-{[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-N-[(4-{[(2R)-1-(phenylsulfanyl)-4-(1-piperazinyl)-2-butanyl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamid
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Molecular Formula
C47H56ClF3N6O5S3
Molecular Weight
973.65 g/mol
SMILES
CC1(C)CCC(=C(C1)CN1CCN(CC1)C1C=CC(=CC=1)C(=O)NS(=O)(=O)C1C=CC(N[C@@H](CSC2C=CC=CC=2)CCN2CCNCC2)=C(C=1)S(=O)(=O)C(F)(F)F)C1C=CC(Cl)=CC=1
InChIKey
CRPNZDFOWRFBLZ-KXQOOQHDSA-N
Last Updated: 2026-03-23 08:16
![4-(4-{[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl}-1-piperazinyl)-N-[(4-{[(2R)-1-(phenylsulfanyl)-4-(1-piperazinyl)-2-butanyl]amino}-3-[(trifluoromethyl)sulfonyl]phenyl)sulfonyl]benzamid
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