Compound Q&A
How is (1R,2S,4R,5S)-3-Oxatricyclo[3.2.1.0~2,4~]octane (CAS: 3146-39-2) typically synthesized?
Answer
![(1R,2S,4R,5S)-3-Oxatricyclo[3.2.1.0~2,4~]octane](https://static.chemtradehub.com/structs/314/3146-39-2-953a.webp "(1R,2S,4R,5S)-3-Oxatricyclo[3.2.1.0~2,4~]octane")
(1R,2S,4R,5S)-3-Oxatricyclo[3.2.1.0~2,4~]octane can be synthesized via a ring-opening reaction of (S)-2,3,4,5-tetrahydroxy-1-cyclopentene-1-one. This reaction is typically catalyzed by a strong acid such as hydrochloric acid, with a yield of up to 90%. The reaction is highly selective, and the stereochemistry is preserved during the synthesis.
About
CAS No
3146-39-2
English Name
(1R,2S,4R,5S)-3-Oxatricyclo[3.2.1.0~2,4~]octane
Molecular Formula
C7H10O
Molecular Weight
110.16 g/mol
SMILES
C1CC2CC1C3C2O3
InChIKey
OHNNZOOGWXZCPZ-RNGGSSJXSA-N
Last Updated: 2026-03-23 04:12
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![(1R,2S,4R,5S)-3-Oxatricyclo[3.2.1.0~2,4~]octane — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}