Compound Q&A
How is (1R,3S,7R,8R,8aS)-8-{2-[(2R,4S)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate (CAS: 79902-62-8) typically synthesized?
Answer
![(1R,3S,7R,8R,8aS)-8-{2-[(2R,4S)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate](https://static.chemtradehub.com/structs/799/79902-62-8-7614.webp "(1R,3S,7R,8R,8aS)-8-{2-[(2R,4S)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate")
The compound is synthesized by a multi-step process involving alkylation of naphthalene and subsequent derivatization. Commonly, a Grignard reagent is used for the alkylation step, followed by ring expansion and esterification. The reaction yields are moderate to high, and the process is carried out under inert atmosphere to prevent decomposition.
About
CAS No
79902-62-8
English Name
(1R,3S,7R,8R,8aS)-8-{2-[(2R,4S)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate
Molecular Formula
C25H38O5
Molecular Weight
444.61 g/mol
SMILES
C=C(C)CC(C)(C)C(O[C@H]1C[C@@H](C)C=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(O3)=O)[C@@]12[H])=O
InChIKey
RYMZZMVNJRMUDD-MKPQAFFTSA-N
Last Updated: 2026-03-23 04:12
![(1R,3S,7R,8R,8aS)-8-{2-[(2R,4S)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydro-1-naphthalenyl 2,2-dimethylbutanoate — Shanghai Yuyeh Biotechnology Co., Ltd.](https://static.chemtradehub.com/suppliers/67ce9f132b2de6e8e95a48fe/67ce9f132b2de6e8e95a48fe-logo.webp){kind=logo}