Compound Q&A

How is ethyl 2-(1H-1,2,3-triazol-1-yl)acetate (CAS: 4314-21-0) typically synthesized?

Answer

ethyl 2-(1H-1,2,3-triazol-1-yl)acetate
Ethyl 2-(1H-1,2,3-triazol-1-yl)acetate (CAS: 4314-21-0) can be synthesized via the reaction of 2-(1H-1,2,3-triazol-1-yl)acetic acid with ethyl chloroformate in the presence of a base like triethylamine. The process involves nucleophilic displacement, and the product is isolated by column chromatography. The yield is typically around 85%, and the reaction is highly selective.

About

CAS No 4314-21-0
English Name ethyl 2-(1H-1,2,3-triazol-1-yl)acetate
Molecular Formula C6H9N3O2
Molecular Weight 155.16 g/mol
SMILES CCOC(=O)CN1C=CN=N1
InChIKey DAWFJGMMMBJQBB-UHFFFAOYSA-N
Last Updated: 2026-03-23 00:14

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