Compound Q&A

How is Ethyl (2Z)-2-cyano-3-hydroxy-2-butenoate (CAS: 794574-92-8) typically synthesized?

Answer

Ethyl (2Z)-2-cyano-3-hydroxy-2-butenoate
Ethyl (2Z)-2-cyano-3-hydroxy-2-butenoate (CAS: 794574-92-8) is typically synthesized via a multi-step reaction involving acylation, cyanation, and hydroxylation. The reaction often uses acetic anhydride for acylation, sodium cyanide for cyanation, and a base like sodium hydroxide for hydroxylation. The yield is around 70-80%, and the reaction is carried out under mild to moderate conditions to ensure selectivity.

About

English Name Ethyl (2Z)-2-cyano-3-hydroxy-2-butenoate
Molecular Formula C7H9NO3
Molecular Weight 144.17 g/mol
SMILES CCOC(=O)/C(=C(/C)\O)/C#N
InChIKey ZCGIXZHJMNCSDQ-WAYWQWQTSA-N
Last Updated: 2026-03-22 14:59

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