Compound Q&A

How is 1,2-di-(2E,4E-octadecadienoyl)-sn-glycero-3-phosphocholine (CAS: 95721-44-1) typically synthesized?

Answer

1,2-di-(2E,4E-octadecadienoyl)-sn-glycero-3-phosphocholine
This compound is typically synthesized through the esterification of phosphatidylcholine with octadecadienoic acid derivatives under mild conditions. The reaction is facilitated by a catalytic amount of a strong acid or base. The yield is generally around 85-90%, and the selectivity towards the desired product is high, making it a suitable method for large-scale production.

About

CAS No 95721-44-1
English Name 1,2-di-(2E,4E-octadecadienoyl)-sn-glycero-3-phosphocholine
Molecular Formula C44H80NO8P
Molecular Weight 782.08 g/mol
SMILES CCCCCCCCCCCCCC=CC=CC(=O)OCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)C=CC=CCCCCCCCCCCCCC
InChIKey UZBZIHXSLHMNPD-DFTZLCQUSA-N
Last Updated: 2026-03-22 14:59

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