Compound Q&A
How is 2-{4-[(E)-2-Chloro-1,2-diphenylvinyl]phenoxy}-N,N-diethylethanamine (CAS: 15690-57-0) typically synthesized?
Answer
![2-{4-[(E)-2-Chloro-1,2-diphenylvinyl]phenoxy}-N,N-diethylethanamine](https://static.chemtradehub.com/structs/156/15690-57-0-6bd8.webp "2-{4-[(E)-2-Chloro-1,2-diphenylvinyl]phenoxy}-N,N-diethylethanamine")
2-{4-[(E)-2-Chloro-1,2-diphenylvinyl]phenoxy}-N,N-diethylethanamine can be synthesized through a multistep process involving the formation of a chloro-vinyl intermediate, followed by coupling with a phenoxy group and N,N-diethylation. The reaction typically requires the use of catalytic amounts of palladium(II) acetate and triphenylphosphine as a ligand, with a yield of around 70%.
About
CAS No
15690-57-0
English Name
2-{4-[(E)-2-Chloro-1,2-diphenylvinyl]phenoxy}-N,N-diethylethanamine
Molecular Formula
C26H28ClNO
Molecular Weight
405.97 g/mol
SMILES
CCN(CC)CCOC1=CC=C(C=C1)C(=C(C2=CC=CC=C2)Cl)C3=CC=CC=C3
InChIKey
GKIRPKYJQBWNGO-OCEACIFDSA-N
Last Updated: 2026-03-20 02:47
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